Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCZ | Q05513 | 6/20 | 0.43 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.42 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGAV | P06756 | 1/20 | 0.40 |
| ▸ | CTSA | P10619 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL657578 | 0.99 | PRKCZ (0.42) | PRKCZFFAR2CYP26A1KDM4EPOLB | |
| SCHEMBL2356968 | 0.91 | PRKCZ (0.53) | PRKCZFFAR2POLBRAB9AHSD17B10 | |
| SCHEMBL2302338 | 0.78 | PRKCZ (0.46) | PRKCZRAB9AHSD17B10LMNATSHR | |
| Hydrochloric Acid SCHEMBL658248 | 0.77 | PRKCZ (0.45) | PRKCZRAB9AHSD17B10LMNATSHR | |
| SCHEMBL659483 | 0.75 | PRKCZ (0.72) | PRKCZKDM4ERAB9AHSD17B10LMNA | |
| Hydrochloric Acid SCHEMBL657199 | 0.74 | PRKCZ (0.71) | PRKCZKDM4ERAB9AHSD17B10LMNA | |
| SCHEMBL5794188 | 0.71 | SCN10A (0.45) | PRKCZRAB9AHSD17B10 | |
| SCHEMBL9893032 | 0.70 | LMNA (0.63) | FFAR2KDM4EPOLBRAB9AHSD17B10 | |
| SCHEMBL7878249 | 0.70 | FFAR2 (0.54) | PRKCZFFAR2KDM4ERAB9AHSD17B10 | |
| SCHEMBL14408241 | 0.70 | GABBR2 (0.56) | CYP26A1KDM4EHSD17B10LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2349999-A1 | ALLOSTERIC PROTEIN KINASE MODULATORS | Universität des Saarlandes (DE) | 2011-08-03 | — | — | EP | claimed |
| WO-2010043711-A1 | ALLOSTERIC PROTEIN KINASE MODULATORS | UNIVERSITAET DES SAARLANDES (DE) | 2010-04-22 | — | — | WO | claimed |
| EP-2349999-A1 | ALLOSTERIC PROTEIN KINASE MODULATORS | Universität des Saarlandes (DE) | 2011-08-03 | — | — | EP | disclosed |
| WO-2010043711-A1 | ALLOSTERIC PROTEIN KINASE MODULATORS | UNIVERSITAET DES SAARLANDES (DE) | 2010-04-22 | — | — | WO | disclosed |