Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR2 | O15552 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | PRKCZ | Q05513 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | GABBR2 | O75899 | 3/20 | 0.45 |
| ▸ | GABBR1 | Q9UBS5 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6935294 | 0.83 | KDM4E (0.41) | FFAR2RAB9ANPC1KDM4EPRKCZ | |
| SCHEMBL3538175 | 0.83 | RAB9A (0.55) | FFAR2RAB9ANPC1KDM4ESMN1; SMN2 | |
| SCHEMBL2302990 | 0.80 | PRKCZ (0.76) | RAB9ANPC1KDM4EPRKCZSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL658839 | 0.79 | PRKCZ (0.74) | RAB9ANPC1KDM4EPRKCZSMN1; SMN2 | |
| SCHEMBL6763140 | 0.74 | ITGAV (0.56) | FFAR2RAB9ANPC1KDM4EPRKCZ | |
| SCHEMBL3541921 | 0.73 | RAB9A (0.62) | RAB9ANPC1SMN1; SMN2HTTTP53 | |
| SCHEMBL8328333 | 0.73 | ALPL (0.64) | RAB9ANPC1SMN1; SMN2HTTTP53 | |
| SCHEMBL7876392 | 0.72 | ITGB3 (0.65) | FFAR2KDM4EGABBR2GABBR1LMNA | |
| SCHEMBL3543587 | 0.71 | FFAR2 (0.54) | FFAR2RAB9ANPC1KDM4ESMN1; SMN2 | |
| SCHEMBL28972118 | 0.71 | FFAR2 (0.47) | FFAR2RAB9ANPC1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326403-B1 | CARDIOVASCULAR DISORDERS | MERCK PATENT GESELLSCHAFT MIT (DE) | 2001-12-04 | — | — | US | disclosed |