Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2356362 | 0.72 | NFKB1 (0.47) | MAPTHTTRECQLCYP1A2CYP3A4 | |
| SCHEMBL7666711 | 0.68 | MAPK1 (0.56) | MAPTHTTRECQLCYP1A2CYP3A4 | |
| SCHEMBL11154445 | 0.67 | TSHR (0.43) | MEN1KMT2AKDM4E | |
| SCHEMBL11153799 | 0.66 | MEN1 (0.35) | MEN1KMT2A | |
| SCHEMBL23706268 | 0.65 | ALDH1A1 (0.46) | MAPTHTTRECQLCYP1A2CYP3A4 | |
| SCHEMBL7369247 | 0.65 | MAPT (0.52) | MAPTHTTRECQLCYP1A2CYP3A4 | |
| SCHEMBL17221828 | 0.65 | MAPT (0.43) | MAPTHTTRECQLCYP1A2CYP3A4 | |
| SCHEMBL16423309 | 0.65 | CASP3 (0.40) | MAPTRECQLCASP3ALDH1A1MEN1 | |
| SCHEMBL20529800 | 0.64 | HDAC6 (0.62) | MAPT | |
| SCHEMBL11100770 | 0.64 | CA12 (0.58) | RECQLCASP3ALDH1A1MEN1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3095780-A1 | PESTICIDAL ARYLPYRROLIDINES | Bayer Intellectual Property GmbH (DE) | 2016-11-23 | — | — | EP | disclosed |
| US-9271499-B2 | Pesticidal arylpyrrolidines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-03-01 | — | — | US | disclosed |
| US-9266830-B2 | Pesticidal arylpyrrolidines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-02-23 | — | — | US | disclosed |
| US-20150073139-A1 | Pesticidal Arylpyrrolidines | BAYER CROPSCIENCE AG (DE) | 2015-03-12 | — | — | US | disclosed |
| US-20150011553-A1 | Pesticidal Arylpyrrolidines | BAYER CROPSCIENCE AG (DE) | 2015-01-08 | — | — | US | disclosed |
| US-8785647-B2 | Pesticidal arylpyrrolidines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-07-22 | — | — | US | disclosed |
| US-20130310408-A1 | Pesticidal Arylpyrrolidines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-11-21 | — | — | US | disclosed |
| EP-2349994-A1 | PESTICIDAL (HETERO) ARYLPYRROLIDINES | BAYER CROPSCIENCE AG (DE) | 2011-08-03 | — | — | EP | disclosed |
| WO-2010043315-A1 | PESTICIDAL (HETERO) ARYLPYRROLIDINES | BAYER CROPSCIENCE AG (DE) | 2010-04-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150011553-A1 | Pesticidal Arylpyrrolidines | DDT, AADAC, AHR | MAPT 4207/4885HTT 1216/4885RECQL 3756/4885 |
| US-20150073139-A1 | Pesticidal Arylpyrrolidines | DDT, ACHE, QDPR | MAPT 3780/4885HTT 1751/4885RECQL 4166/4885 |
| US-20130310408-A1 | Pesticidal Arylpyrrolidines | DDT, ACHE, QDPR | MAPT 3780/4885HTT 1751/4885RECQL 4166/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.