Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 2/20 | 0.47 |
| ▸ | JUN | P05412 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | XPO1 | O14980 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 6/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | ATF1 | P18846 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17396444 | 0.82 | ALDH1A1 (0.46) | NFKB1JUNNFKB2RELAALDH1A1 | |
| SCHEMBL542033 | 0.78 | CNR2 (0.54) | GRM5CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL21528071 | 0.72 | CASP3 (0.57) | ALDH1A1MEN1PKMKMT2AHTT | |
| SCHEMBL2359979 | 0.72 | MAPT (0.40) | ALDH1A1MEN1PKMKMT2AGRM5 | |
| SCHEMBL11100770 | 0.69 | CA12 (0.58) | ALDH1A1MEN1PKMKMT2AGRM5 | |
| SCHEMBL23528010 | 0.69 | KMT2A (0.50) | ALDH1A1MEN1PKMKMT2AGRM5 | |
| SCHEMBL18669233 | 0.69 | CHRM5 (0.50) | ALDH1A1MEN1KMT2AGRM5HTT | |
| SCHEMBL16635417 | 0.69 | MAPT (0.40) | NFKB1JUNNFKB2RELAALDH1A1 | |
| SCHEMBL6160194 | 0.68 | KMT2A (0.53) | NFKB1JUNNFKB2RELAALDH1A1 | |
| SCHEMBL24424828 | 0.68 | TSHR (0.42) | ALDH1A1MEN1PKMKMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3095780-A1 | PESTICIDAL ARYLPYRROLIDINES | Bayer Intellectual Property GmbH (DE) | 2016-11-23 | — | — | EP | disclosed |
| US-9271499-B2 | Pesticidal arylpyrrolidines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-03-01 | — | — | US | disclosed |
| US-9266830-B2 | Pesticidal arylpyrrolidines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-02-23 | — | — | US | disclosed |
| US-20150073139-A1 | Pesticidal Arylpyrrolidines | BAYER CROPSCIENCE AG (DE) | 2015-03-12 | — | — | US | disclosed |
| US-20150011553-A1 | Pesticidal Arylpyrrolidines | BAYER CROPSCIENCE AG (DE) | 2015-01-08 | — | — | US | disclosed |
| US-8785647-B2 | Pesticidal arylpyrrolidines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-07-22 | — | — | US | disclosed |
| US-20130310408-A1 | Pesticidal Arylpyrrolidines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-11-21 | — | — | US | disclosed |
| US-8450483-B2 | Pesticidal arylpyrrolidines | BAYER CROPSCIENCE AG (DE) | 2013-05-28 | — | — | US | disclosed |
| EP-2349994-A1 | PESTICIDAL (HETERO) ARYLPYRROLIDINES | BAYER CROPSCIENCE AG (DE) | 2011-08-03 | — | — | EP | disclosed |
| US-20100216792-A1 | Pesticidal arylpyrrolidines | BAYER CROPSCIENCE AG (DE) | 2010-08-26 | — | — | US | disclosed |
| WO-2010043315-A1 | PESTICIDAL (HETERO) ARYLPYRROLIDINES | BAYER CROPSCIENCE AG (DE) | 2010-04-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150011553-A1 | Pesticidal Arylpyrrolidines | DDT, AADAC, AHR | NFKB1 3198/4885JUN 4230/4885NFKB2 3819/4885 |
| US-20100216792-A1 | Pesticidal arylpyrrolidines | DDT, AADAC, AHR | NFKB1 3198/4885JUN 4230/4885NFKB2 3819/4885 |
| US-20150073139-A1 | Pesticidal Arylpyrrolidines | DDT, ACHE, QDPR | NFKB1 2969/4885JUN 3577/4885NFKB2 3921/4885 |
| US-20130310408-A1 | Pesticidal Arylpyrrolidines | DDT, ACHE, QDPR | NFKB1 2969/4885JUN 3577/4885NFKB2 3921/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.