Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 3/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.36 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.36 |
| ▸ | PDE5A | O76074 | 2/20 | 0.34 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | BCR | P11274 | 1/20 | 0.32 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.32 |
| ▸ | CDK4 | P11802 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23601707 | 0.86 | PDE5A (0.42) | CSNK2A1CSNK2A2CSNK2BPDE5A | |
| SCHEMBL23601723 | 0.84 | PDE5A (0.36) | CHEK1PDE5AMAPTMEN1KMT2A | |
| SCHEMBL23601069 | 0.82 | PDE5A (0.37) | CSNK2A1CSNK2A2CSNK2BPDE5AMAPT | |
| SCHEMBL23601722 | 0.80 | PDE5A (0.36) | CSNK2A1CSNK2A2CSNK2BPDE5A | |
| SCHEMBL23601557 | 0.78 | LMNA (0.40) | LMNAHPGD | |
| SCHEMBL23601391 | 0.78 | EGFR (0.46) | — | |
| SCHEMBL29909858 | 0.77 | CSNK2A1 (0.36) | CHEK1CSNK2A1CSNK2A2CSNK2BPDE5A | |
| SCHEMBL23577892 | 0.77 | CSNK2A1 (0.36) | CHEK1CSNK2A1CSNK2A2CSNK2BPDE5A | |
| SCHEMBL23601519 | 0.76 | ABCG2 (0.46) | KDM4EMAPTMEN1LMNAKMT2A | |
| SCHEMBL23601210 | 0.75 | PDE5A (0.36) | PDE5AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021130638-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES, INC. (JP) | 2021-07-01 | — | — | WO | disclosed |