Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.34 |
| ▸ | PDE5A | O76074 | 2/20 | 0.33 |
| ▸ | EGFR | P00533 | 3/20 | 0.32 |
| ▸ | KDR | P35968 | 2/20 | 0.32 |
| ▸ | CLK1 | P49759 | 1/20 | 0.32 |
| ▸ | CLK2 | P49760 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.32 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23601230 | 0.90 | SIGMAR1 (0.41) | ABCG2PDGFRBPDE5AEGFRKDR | |
| SCHEMBL23600997 | 0.87 | PDGFRB (0.34) | ABCG2PDGFRBPDE5AEGFRKDR | |
| SCHEMBL23601204 | 0.79 | KDM4C (0.38) | ABCG2PDE5ACLK1CLK2DYRK1A | |
| SCHEMBL23601333 | 0.77 | ADORA3 (0.35) | ABCG2PDE5ACLK1CLK2DYRK1A | |
| SCHEMBL23601809 | 0.77 | LMNA (0.41) | PDGFRBPDE5AEGFRKDR | |
| SCHEMBL23600980 | 0.77 | EGFR (0.36) | ABCG2PDGFRBPDE5AEGFRKDR | |
| SCHEMBL29909821 | 0.75 | SMN1; SMN2 (0.37) | ABCG2PDGFRBPDE5AEGFRKDR | |
| SCHEMBL23577471 | 0.75 | SMN1; SMN2 (0.37) | ABCG2PDGFRBPDE5AEGFRKDR | |
| SCHEMBL23601500 | 0.75 | KCNA3 (0.32) | PDE5A | |
| SCHEMBL23601069 | 0.75 | PDE5A (0.37) | PDGFRBPDE5AEGFRKDRDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021130638-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES, INC. (JP) | 2021-07-01 | — | — | WO | disclosed |