Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 4/20 | 0.38 |
| ▸ | HTR2C | P28335 | 3/20 | 0.33 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR7 | P34969 | 2/20 | 0.33 |
| ▸ | DRD3 | P35462 | 2/20 | 0.33 |
| ▸ | HTR6 | P50406 | 2/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | GAA | P10253 | 4/20 | 0.32 |
| ▸ | PDE5A | O76074 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | PMM2 | O15305 | 1/20 | 0.32 |
| ▸ | MPI | P34949 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23601230 | 0.80 | SIGMAR1 (0.41) | ABCG2PDE5AMAPTMEN1KMT2A | |
| SCHEMBL23601333 | 0.80 | ADORA3 (0.35) | ABCG2PDE5AMAPK1MEN1KMT2A | |
| SCHEMBL23601745 | 0.79 | ABCG2 (0.36) | ABCG2PDE5ACLK1CLK2DYRK1A | |
| SCHEMBL23600997 | 0.77 | PDGFRB (0.34) | ABCG2PDE5ACLK1CLK2DYRK1A | |
| SCHEMBL29909385 | 0.76 | MAPT (0.42) | KDM4CHTR2CHTR1AHTR2AHTR7 | |
| SCHEMBL23577273 | 0.76 | MAPT (0.42) | KDM4CHTR2CHTR1AHTR2AHTR7 | |
| SCHEMBL23601809 | 0.75 | LMNA (0.41) | PDE5AMAPTHPGD | |
| SCHEMBL23600980 | 0.75 | EGFR (0.36) | ABCG2KDM4EPDE5AALDH1A1MAPT | |
| SCHEMBL23601069 | 0.73 | PDE5A (0.37) | PDE5AMAPTDYRK1A | |
| SCHEMBL23601707 | 0.72 | PDE5A (0.42) | ABCG2PDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021130638-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES, INC. (JP) | 2021-07-01 | — | — | WO | disclosed |