Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 4/20 | 0.38 |
| ▸ | EGFR | P00533 | 3/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.38 |
| ▸ | FLT1 | P17948 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 2/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.35 |
| ▸ | PDE5A | O76074 | 2/20 | 0.35 |
| ▸ | CSF1R | P07333 | 1/20 | 0.34 |
| ▸ | CHKA | P35790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23600980 | 0.88 | EGFR (0.36) | LMNAMAPTHPGDKDREGFR | |
| SCHEMBL23601230 | 0.78 | SIGMAR1 (0.41) | LMNAMAPTTSHRKDREGFR | |
| SCHEMBL23601057 | 0.78 | L3MBTL1 (0.38) | — | |
| SCHEMBL23601069 | 0.78 | PDE5A (0.37) | MAPTKDREGFRPDGFRBPDE5A | |
| SCHEMBL23601745 | 0.77 | ABCG2 (0.36) | KDREGFRPDGFRBPDE5A | |
| SCHEMBL23601707 | 0.77 | PDE5A (0.42) | KDREGFRPDGFRBPDE5A | |
| SCHEMBL23601199 | 0.77 | PDE5A (0.39) | MAPTKDREGFRPDGFRBPDE5A | |
| SCHEMBL23601722 | 0.76 | PDE5A (0.36) | PDE5A | |
| SCHEMBL23601194 | 0.73 | PDE5A (0.41) | KDREGFRPDGFRBPDE5A | |
| SCHEMBL23601124 | 0.73 | KDM4E (0.37) | MAPTHPGDTSHREGFRCSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021130638-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES, INC. (JP) | 2021-07-01 | — | — | WO | disclosed |