Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.37 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.37 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.37 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23608967 | 0.94 | QPCT (0.39) | CYP19A1LMNASMN1; SMN2PTK2KCNQ3 | |
| SCHEMBL23608966 | 0.80 | CYP19A1 (0.40) | CYP19A1LMNASMN1; SMN2PTK2NAMPT | |
| SCHEMBL29973640 | 0.80 | CYP19A1 (0.40) | CYP19A1LMNASMN1; SMN2PTK2NAMPT | |
| SCHEMBL23608953 | 0.77 | CYP19A1 (0.38) | CYP19A1LMNASMN1; SMN2PTK2NAMPT | |
| SCHEMBL23608948 | 0.77 | GPR55 (0.47) | CYP19A1LMNASMN1; SMN2NAMPTCYP1A2 | |
| SCHEMBL30406696 | 0.75 | NTRK1 (0.35) | CYP19A1LMNASMN1; SMN2PTK2NAMPT | |
| SCHEMBL23608983 | 0.75 | CYP19A1 (0.43) | CYP19A1LMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL23608949 | 0.74 | CYP19A1 (0.44) | CYP19A1LMNANAMPTKDM4EALDH1A1 | |
| SCHEMBL30406745 | 0.74 | CACNA1B (0.35) | CYP19A1LMNAPTK2NAMPTCYP1A2 | |
| SCHEMBL23608959 | 0.73 | SMN1; SMN2 (0.42) | CYP19A1LMNASMN1; SMN2NAMPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230117592-A1 | LIPOXYGENASE INHIBITORS | SRI INTERNATIONAL (US) | 2023-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230117592-A1 | LIPOXYGENASE INHIBITORS | ALOX15B, ALOX12, ALOX5 | CYP19A1 153/4885LMNA 1170/4885SMN1; SMN2 243/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.