SCHEMBL23608951

SCHEMBL23608951

c1cc(NCCCn2cncn2)cc(NC2CCCCC2)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CSNK2A2 P19784 1/20 0.44
FGFR2 P21802 1/20 0.44
KDR P35968 1/20 0.44
CSNK1A1 P48729 1/20 0.44
CSNK1D P48730 1/20 0.44
CSNK1E P49674 1/20 0.44
GSK3A P49840 1/20 0.44
GSK3B P49841 1/20 0.44
CSNK2B P67870 1/20 0.44
CSNK2A1 P68400 1/20 0.44
CSNK1G2 P78368 1/20 0.44
CSNK1G1 Q9HCP0 1/20 0.44
TSHR P16473 1/20 0.37
MAPK1 P28482 1/20 0.36
ALDH1A1 P00352 2/20 0.36
HPGD P15428 1/20 0.36
ALOX15 P16050 1/20 0.36
TLR9 Q9NR96 1/20 0.36
KDM4E B2RXH2 3/20 0.36
IDH1 O75874 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23608891 0.88 FPR3 (0.40) CSNK2A2FGFR2KDRCSNK1A1CSNK1D
SCHEMBL23609408 0.86 CSNK2A2 (0.36) CSNK2A2FGFR2KDRCSNK1A1CSNK1D
SCHEMBL23608955 0.78 IRAK4 (0.33) MAPK1ALDH1A1KDM4EIDH1MEN1
SCHEMBL23609484 0.76 HPGDS (0.38) CSNK2A2FGFR2KDRCSNK1A1CSNK1D
SCHEMBL23609770 0.76 CSNK2A2 (0.38) CSNK2A2FGFR2KDRCSNK1A1CSNK1D
SCHEMBL23875506 0.76 MAPT (0.51) CSNK2A2FGFR2KDRCSNK1A1CSNK1D
SCHEMBL23609264 0.75 SMN1; SMN2 (0.42) TSHRMAPK1ALDH1A1HPGDALOX15
SCHEMBL3427795 0.71 KDM4E (0.49) TSHRMAPK1ALDH1A1ALOX15KDM4E
SCHEMBL23609076 0.70 CSNK2A2 (0.45) CSNK2A2FGFR2KDRCSNK1A1CSNK1D
SCHEMBL6965842 0.69 CYP19A1 (0.54) CSNK2A2FGFR2KDRCSNK1A1CSNK1D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230117592-A1 LIPOXYGENASE INHIBITORS SRI INTERNATIONAL (US) 2023-04-20 US disclosed
WO-2021133689-A2 LIPOXYGENASE INHIBITORS SRI INTERNATIONAL (US) 2021-07-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230117592-A1 LIPOXYGENASE INHIBITORS ALOX15B, ALOX12, ALOX5 CSNK2A2 2314/4885FGFR2 3460/4885KDR 4181/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.