Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 2/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23628809 | 0.88 | KMT2A (0.53) | KMT2AALOX5LMNAMAPK1RAB9A | |
| SCHEMBL4590819 | 0.79 | KMT2A (0.56) | KMT2AALOX5LMNAMAPK1RAB9A | |
| SCHEMBL28769527 | 0.78 | ALOX5 (0.56) | KMT2AALOX5LMNAMAPK1RAB9A | |
| SCHEMBL27045678 | 0.77 | KMT2A (0.49) | KMT2AALOX5LMNAMAPK1RAB9A | |
| SCHEMBL23628857 | 0.76 | ALDH1A1 (0.43) | KMT2ALMNANPC1ALDH1A1MAPT | |
| SCHEMBL27045816 | 0.74 | KMT2A (0.53) | KMT2AALOX5LMNAMAPK1RAB9A | |
| SCHEMBL27045702 | 0.74 | LMNA (0.56) | KMT2AALOX5LMNAMAPK1RAB9A | |
| SCHEMBL4742174 | 0.74 | KMT2A (0.59) | KMT2AALOX5LMNAMAPK1RAB9A | |
| SCHEMBL9891898 | 0.74 | LMNA (0.69) | KMT2AALOX5LMNAMAPK1RAB9A | |
| SCHEMBL4590880 | 0.74 | KMT2A (0.59) | KMT2AALOX5LMNAMAPK1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12030875-B2 | EIF4E inhibitors and uses thereof | PIC Therapeutics, Inc. (US) | 2024-07-09 | — | — | US | disclosed |
| EP-3846793-B1 | EIF4E INHIBITORS AND USES THEREOF | PIC THERAPEUTICS INC (US) | 2024-01-24 | — | — | EP | disclosed |
| US-20220089587-A1 | EIF4E INHIBITORS AND USES THEREOF | PIC Therapeutics, Inc. | 2022-03-24 | — | — | US | disclosed |
| CN-113164419-A | EIF4E inhibitors and uses thereof | 皮克医疗公司 | 2021-07-23 | — | — | CN | disclosed |
| EP-3846793-A1 | EIF4E INHIBITORS AND USES THEREOF | PIC Therapeutics, Inc. (US) | 2021-07-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12030875-B2 | EIF4E inhibitors and uses thereof | EIF4E, EIF4EBP1, EIF4A1 | KMT2A 1710/4885ALOX5 4250/4885LMNA 2297/4885 |
| US-20220089587-A1 | EIF4E INHIBITORS AND USES THEREOF | EIF4E, EIF4EBP1, EEF2K | KMT2A 1533/4885ALOX5 3543/4885LMNA 2618/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.