Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR1 | P30872 | 1/20 | 0.40 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.40 |
| ▸ | CTSC | P53634 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | FAP | Q12884 | 1/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | AMPD2 | Q01433 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23630306 | 0.75 | SSTR1 (0.46) | SSTR1SSTR4MEN1KMT2APOLB | |
| SCHEMBL11296862 | 0.74 | OPRM1 (0.49) | SSTR1SSTR4MEN1KMT2APOLB | |
| SCHEMBL9768235 | 0.74 | SSTR1 (0.48) | SSTR1SSTR4MEN1KMT2APOLB | |
| SCHEMBL23630299 | 0.73 | HSD11B1 (0.47) | KMT2AALDH1A1L3MBTL1LMNAHTT | |
| SCHEMBL9768219 | 0.72 | GSK3B (0.44) | SSTR1SSTR4MEN1KMT2APOLB | |
| SCHEMBL23635324 | 0.72 | SSTR1 (0.36) | SSTR1SSTR4MEN1KMT2APOLB | |
| SCHEMBL23630295 | 0.71 | ALDH1A1 (0.40) | SSTR1SSTR4CTSCMEN1KMT2A | |
| SCHEMBL28521200 | 0.70 | CNR2 (0.45) | CTSCMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL9768233 | 0.68 | ATF4 (0.54) | MEN1KMT2APOLBNPC1LMNA | |
| SCHEMBL6831516 | 0.68 | CA1 (0.50) | ALDH1A1NPC1L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021142420-A1 | PYRAZOLO[1,5-a]PYRIMIDIN-7(4H)-ONE INHIBITORS OF DYNEIN | KAPOOR TARUN M (US) | 2021-07-15 | — | — | WO | disclosed |