Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTSR1 | P30989 | 4/20 | 0.60 |
| ▸ | KRAS | P01116 | 7/20 | 0.53 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.46 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23631602 | 0.89 | KDM4E (0.48) | NTSR1KRASPSMB1PSMB5KMT2A | |
| SCHEMBL31238612 | 0.87 | NTSR1 (0.58) | NTSR1KRASPSMB1PSMB5HTR2A | |
| SCHEMBL31238628 | 0.85 | NTSR1 (0.56) | NTSR1KRASPSMB1PSMB5HTR2A | |
| SCHEMBL418013 | 0.84 | KMT2A (0.60) | NTSR1KRASHTR2AHTR2CKMT2A | |
| SCHEMBL6138108 | 0.80 | KMT2A (0.69) | NTSR1KMT2AKDM4EALDH1A1GLA | |
| SCHEMBL23631588 | 0.80 | KRAS (0.56) | NTSR1KRASKMT2AALDH1A1HTT | |
| SCHEMBL31602786 | 0.78 | KMT2A (0.65) | NTSR1KMT2AKDM4EALDH1A1GLA | |
| SCHEMBL23631622 | 0.77 | PSMB1 (0.47) | NTSR1KRASPSMB1PSMB5KDM4E | |
| SCHEMBL24480089 | 0.77 | ALDH1A1 (0.62) | NTSR1KRASKDM4EALDH1A1HPGD | |
| SCHEMBL2008953 | 0.77 | HTR2A (0.55) | NTSR1KRASHTR2AHTR2CKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210214359-A1 | Compounds and Methods for Treating Bacterial Infections | UNIV NEW YORK (US) | 2021-07-15 | — | — | US | claimed |
| US-20210214359-A1 | Compounds and Methods for Treating Bacterial Infections | UNIV NEW YORK (US) | 2021-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210214359-A1 | Compounds and Methods for Treating Bacterial Infections | CBS, MPO, QSOX1 | NTSR1 2656/4885KRAS 1973/4885PSMB1 3885/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.