SCHEMBL23635271

SCHEMBL23635271

COC(=O)c1cc(CC(C)C)ccc1NC(C)=O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.47
KMT2A Q03164 2/20 0.44
CYP2C19 P33261 2/20 0.44
MEN1 O00255 1/20 0.44
CYP1A2 P05177 1/20 0.44
TSHR P16473 2/20 0.43
ALDH1A1 P00352 4/20 0.43
KDM4E B2RXH2 4/20 0.43
GAA P10253 4/20 0.43
HPGD P15428 2/20 0.43
HSD17B10 Q99714 2/20 0.43
ALOX15 P16050 1/20 0.43
LMNA P02545 2/20 0.43
SMN1; SMN2 Q16637 1/20 0.42
ERAP2 Q6P179 1/20 0.42
LNPEP Q9UIQ6 1/20 0.42
TDP1 Q9NUW8 1/20 0.41
CXCR1 P25024 1/20 0.40
CXCR2 P25025 1/20 0.40
CYP2C9 P11712 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26046942 0.85 RAB9A (0.49) MAPTKMT2ACYP2C19MEN1CYP1A2
SCHEMBL23635268 0.83 KDM4E (0.57) MAPTKMT2ACYP2C19MEN1CYP1A2
SCHEMBL7854729 0.82 KDM4E (0.50) MAPTTSHRALDH1A1KDM4EGAA
SCHEMBL8888175 0.81 ALDH1A1 (0.44) MAPTKMT2ACYP2C19MEN1CYP1A2
SCHEMBL8886569 0.81 CYP4A11 (0.50) MAPTKMT2ACYP2C19MEN1CYP1A2
SCHEMBL3428272 0.79 TSHR (0.48) MAPTKMT2AMEN1TSHRALDH1A1
SCHEMBL8080032 0.79 MAPT (0.64) MAPTTSHRALDH1A1KDM4EGAA
SCHEMBL1796093 0.78 XDH (0.50) KMT2ACYP2C19MEN1CYP1A2TSHR
SCHEMBL14513563 0.78 HPGD (0.52) MAPTTSHRALDH1A1KDM4EGAA
SCHEMBL11209714 0.78 CA1 (0.51) MAPTKMT2ATSHRALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11649475-B2 Dioxetane compounds and their use for the detection of microorganisms RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2023-05-16 US disclosed
US-20210214766-A1 DIOXETANE COMPOUNDS AND THEIR USE FOR THE DETECTION OF MICROORGANISMS NEMIS TECHNOLOGIES AG (CH) 2021-07-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11649475-B2 Dioxetane compounds and their use for the detection of microorganisms DAXX, LITAF, EDF1 MAPT 4026/4885KMT2A 3558/4885CYP2C19 662/4885
US-20210214766-A1 DIOXETANE COMPOUNDS AND THEIR USE FOR THE DETECTION OF MICROORGANISMS DAXX, CD14, MYADM MAPT 2637/4885KMT2A 3191/4885CYP2C19 404/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.