Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | CHIT1 | Q13231 | 2/20 | 0.38 |
| ▸ | CHIA | Q9BZP6 | 2/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | BRD2 | P25440 | 2/20 | 0.37 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CCNC | P24863 | 1/20 | 0.36 |
| ▸ | CDK8 | P49336 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20564864 | 0.81 | ALDH1A1 (0.37) | HTR3AMAPTGAACHIT1CHIA | |
| SCHEMBL15020704 | 0.76 | IKBKB (0.45) | MAPTGAABRD2BRD3CREBBP | |
| SCHEMBL315186 | 0.73 | HTR3A (0.58) | HTR3AMAPTSLC2A1DRD2MEN1 | |
| SCHEMBL1570625 | 0.68 | KDM1A (0.49) | HTR3AMAPTSLC2A1DRD2MEN1 | |
| SCHEMBL18533598 | 0.67 | HTR3A (0.52) | HTR3AMAPTSLC2A1DRD2MEN1 | |
| Methyl Alcohol SCHEMBL15391253 | 0.67 | DRD2 (0.55) | HTR3AMAPTSLC2A1DRD2MEN1 | |
| SCHEMBL30737651 | 0.67 | MAPK11 (0.43) | MAPTGAADRD2 | |
| Hydrochloric Acid SCHEMBL11838451 | 0.66 | KDM1A (0.47) | HTR3AMAPTSLC2A1DRD2MEN1 | |
| SCHEMBL23630313 | 0.66 | PRKACA (0.57) | MAPTGAACHIT1CHIADRD2 | |
| SCHEMBL23578560 | 0.66 | HTR3A (0.50) | HTR3AMAPTSLC2A1DRD2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021142420-A1 | PYRAZOLO[1,5-a]PYRIMIDIN-7(4H)-ONE INHIBITORS OF DYNEIN | KAPOOR TARUN M (US) | 2021-07-15 | — | — | WO | disclosed |