Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 2/20 | 0.36 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.35 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.32 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2363555 | 0.81 | GRIN2B (0.44) | MAPTKDM4ELMNA | |
| SCHEMBL2365541 | 0.79 | GAA (0.39) | MAPTKDM4EALDH1A1 | |
| SCHEMBL2363548 | 0.76 | KDM4E (0.43) | KDM4ELMNALTA4HALDH1A1 | |
| SCHEMBL2365577 | 0.73 | HRH2 (0.37) | MAPTLTA4HTP53 | |
| SCHEMBL2365494 | 0.73 | ACKR3 (0.45) | LTA4H | |
| SCHEMBL2364770 | 0.72 | GPR119 (0.41) | LTA4H | |
| SCHEMBL2365569 | 0.71 | KCNA5 (0.36) | LTA4H | |
| SCHEMBL2231139 | 0.70 | MET (0.40) | LMNA | |
| SCHEMBL2226186 | 0.68 | MMP2 (0.39) | S1PR1LMNA | |
| SCHEMBL2365345 | 0.67 | ALDH1A1 (0.37) | KDM4EALDH1A1SGMS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011089550-A1 | ALKYL-HETEROCYCLE CARBAMATE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | SANOFI AVENTIS (FR) | 2011-07-28 | — | — | WO | claimed |
| WO-2011089550-A1 | ALKYL-HETEROCYCLE CARBAMATE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | SANOFI AVENTIS (FR) | 2011-07-28 | — | — | WO | disclosed |