Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYBB | P04839 | 1/20 | 0.35 |
| ▸ | NCF1 | P14598 | 1/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.34 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.31 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.31 |
| ▸ | DHPS | P49366 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29778792 | 1.00 | CYBB (0.35) | CYBBNCF1P2RX3P2RX2HTR2A | |
| SCHEMBL26977593 | 0.82 | HTR2A (0.38) | CYBBNCF1P2RX3P2RX2HTR2A | |
| SCHEMBL30731668 | 0.82 | HTR2A (0.38) | CYBBNCF1P2RX3P2RX2HTR2A | |
| SCHEMBL23641526 | 0.82 | CYBB (0.38) | CYBBNCF1TLR8 | |
| SCHEMBL29778785 | 0.82 | CYBB (0.38) | CYBBNCF1TLR8 | |
| SCHEMBL21608777 | 0.81 | P2RX3 (0.36) | P2RX3P2RX2HTR2APIK3CAPIK3CD | |
| SCHEMBL30723514 | 0.81 | P2RX3 (0.36) | P2RX3P2RX2HTR2APIK3CAPIK3CD | |
| SCHEMBL27038877 | 0.79 | P2RX3 (0.35) | P2RX3P2RX2PIK3CAPIK3CDPIK3CG | |
| SCHEMBL30729951 | 0.77 | NUDT1 (0.42) | P2RX3P2RX2 | |
| SCHEMBL27036137 | 0.77 | NUDT1 (0.42) | P2RX3P2RX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112292375-B | Substituted alkoxypyridinyl indole sulfonamides | 优时比制药有限公司 | 2023-12-05 | — | — | CN | disclosed |
| US-20210214337-A1 | SUBSTITUTED ALKOXYPYRIDINYL INDOLSULFONAMIDES | UCB PHARMA GMBH (DE) | 2021-07-15 | — | — | US | disclosed |
| CN-112292375-A | Substituted alkoxypyridylindolesulfonamides | 优时比制药有限公司 | 2021-01-29 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210214337-A1 | SUBSTITUTED ALKOXYPYRIDINYL INDOLSULFONAMIDES | GPR119, GPR17, GPR27 | CYBB 4271/4885NCF1 3953/4885P2RX3 537/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.