SCHEMBL2364326

SCHEMBL2364326

C=CCOP(=O)(OCC=C)C(CC)C(=O)O

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4682326 0.82 CASP1 (0.33)
SCHEMBL262483 0.79 POLB (0.43) TSHR
SCHEMBL10698200 0.76 LAP3 (0.31) TSHR
SCHEMBL4117495 0.75 POLB (0.38) TSHR
SCHEMBL6579012 0.72 LMNA (0.38)
SCHEMBL9278204 0.72 TDP1 (0.31)
SCHEMBL689250 0.71 HTT (0.34)
SCHEMBL2364791 0.71 LPAR3 (0.48)
SCHEMBL15438315 0.71 PKM (0.31)
SCHEMBL5363385 0.70 FOLH1 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8741871-B2 Trehalose compound, method for producing same, and pharmaceutical product containing the compound GLYTECH, INC. (JP) 2014-06-03 US disclosed
US-20110218171-A1 TREHALOSE COMPOUND, METHOD FOR PRODUCING SAME, AND PHARMACEUTICAL PRODUCT CONTAINING THE COMPOUND OTSUKA CHEMICAL CO., LTD. (JP) 2011-09-08 US disclosed
EP-2351764-A1 TREHALOSE COMPOUND, METHOD FOR PRODUCING SAME, AND PHARMACEUTICAL PRODUCT CONTAINING THE COMPOUND Otsuka Chemical Co., Ltd. (JP) 2011-08-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110218171-A1 TREHALOSE COMPOUND, METHOD FOR PRODUCING SAME, AND PHARMACEUTICAL PRODUCT CONTAINING THE COMPOUND TREH, MAN2B1, NFATC1 TSHR 2522/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.