Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 2/20 | 0.34 |
| ▸ | MMP2 | P08253 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29390337 | 0.90 | LMNA (0.35) | LMNACYP2C19MMP1MMP2CA2 | |
| SCHEMBL3899260 | 0.83 | CHRM1 (0.43) | LMNACYP2C19CA2FOLH1MAPK1 | |
| SCHEMBL3900935 | 0.80 | FOLH1 (0.42) | MMP1MMP2CA2CA12CA1 | |
| SCHEMBL262483 | 0.80 | POLB (0.43) | CYP2C19TDP1 | |
| SCHEMBL2984496 | 0.80 | MMP1 (0.33) | LMNAMMP1MMP2CA2CA12 | |
| SCHEMBL10875658 | 0.80 | FOLH1 (0.38) | LMNACYP2C19CA2FOLH1TDP1 | |
| SCHEMBL2983917 | 0.80 | CA1 (0.39) | LMNACYP2C19MMP1MMP2CA2 | |
| SCHEMBL787792 | 0.79 | CA2 (0.44) | LMNACA2CA1MAPK1CHRM1 | |
| SCHEMBL31267408 | 0.79 | MMP8 (0.31) | LMNAMMP8TDP1 | |
| SCHEMBL9184149 | 0.78 | FOLH1 (0.36) | LMNACYP2C19FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2581359-B1 | REAGENT FOR TESTING PURIFICATION CAPACITY OF RADIOACTIVE GAS IN A NUCLEAR POWER PLANT, PREPARATION METHOD THEREOF AND IODIDE FILTER TESTING EQUIPMENT USING THIS REAGENT | CHINA GENERAL NUCLEAR POWER (CN) | 2016-03-30 | — | — | EP | claimed |
| US-9174968-B2 | Pyrimidinone compounds for use in the treatment of diseases or conditions mediated by LP-PLA2 | GLAXO GROUP LIMITED (GB) | 2015-11-03 | — | — | US | disclosed |
| US-20140113922-A1 | COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2014-04-24 | — | — | US | disclosed |
| US-8637536-B2 | Pyrimidinone compounds for use in the treatment of diseases or conditions mediated by Lp-PLA2 | GLAXO GROUP LIMITED (GB) | 2014-01-28 | — | — | US | disclosed |
| US-20130252963-A1 | PYRIMIDINONE COMPOUNDS FOR USE IN THE TREATMENT OF DISEASE OR CONDITIONS MEDIATED BY LP-PLA2 | GLAXO GROUP LIMITED (GB) | 2013-09-26 | — | — | US | disclosed |
| US-20120142717-A1 | COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2012-06-07 | — | — | US | disclosed |
| EP-1169744-B1 | WET-ON-WET COATING METHOD FOR PRODUCING COMPOSITE BODIES THAT ARE SUITABLE FOR USE IN LITHIUM ION BATTERIES | BASF AG (DE) | 2004-06-30 | — | — | EP | disclosed |
| US-20040058965-A1 | Alkanoic acid derivatives process for their production and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-03-25 | — | — | US | disclosed |
| EP-1088007-B1 | COMPOSITIONS SUITABLE FOR ELECTROCHEMICAL CELLS | BASF AG (DE) | 2003-02-26 | — | — | EP | disclosed |
| EP-0970529-B1 | METHOD FOR PRODUCING SHAPED BODIES FOR LITHIUM ION BATTERIES | BASF AG (DE) | 2002-08-28 | — | — | EP | disclosed |
| WO-2000008068-A1 | COMPOSITIONS SUITABLE FOR ELECTROCHEMICAL CELLS | BASF AKTIENGESELLSCHAFT (DE) | 2000-02-17 | — | — | WO | disclosed |
| EP-0970529-A1 | METHOD FOR PRODUCING SHAPED BODIES FOR LITHIUM ION BATTERIES | BASF AKTIENGESELLSCHAFT (DE) | 2000-01-12 | — | — | EP | disclosed |
| WO-1999057161-A1 | COMPOSITIONS SUITABLE FOR ELECTROCHEMICAL CELLS | BASF AKTIENGESELLSCHAFT (DE) | 1999-11-11 | — | — | WO | disclosed |
| WO-1999019921-A1 | MIXTURES WITH Li-CONTAINING SOLIDS SUITABLE AS SOLID ELECTROLYTES OR SEPARATORS FOR ELECTROCHEMICAL CELLS | BASF AKTIENGESELLSCHAFT (DE) | 1999-04-22 | — | — | WO | disclosed |
| WO-1999018621-A1 | MIXTURES WITH SPECIAL SOFTENING AGENTS SUITED AS A SOLID ELECTROLYTE OR SEPARATOR FOR ELECTROCHEMICAL CELLS | BASF AKTIENGESELLSCHAFT (DE) | 1999-04-15 | — | — | WO | disclosed |
| EP-0890196-A1 | MIXTURES SUITABLE AS SOLID ELECTROLYTES OR SEPARATORS FOR ELECTROCHEMICAL CELLS | BASF AKTIENGESELLSCHAFT (DE) | 1999-01-13 | — | — | EP | disclosed |
| WO-1998044576-A1 | METHOD FOR PRODUCING SHAPED BODIES FOR LITHIUM ION BATTERIES | BASF AKTIENGESELLSCHAFT (DE) | 1998-10-08 | — | — | WO | disclosed |
| WO-1997037397-A1 | MIXTURES SUITABLE AS SOLID ELECTROLYTES OR SEPARATORS FOR ELECTROCHEMICAL CELLS | BASF AKTIENGESELLSCHAFT (DE) | 1997-10-09 | — | — | WO | disclosed |
| US-5656709-A | Hybrid material and process for producing the same | KABUSHIKI KAISHA TOYOTA CHUO KENKYUSHO (JP) | 1997-08-12 | — | — | US | disclosed |
| US-5025002-A | Broad spectrum biocide, industrial process systems | BROMINE COMPOUNDS LTD. (IL) | 1991-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140113922-A1 | COMPOUNDS | LIPG, PLA2G1B, ENPP2 | LMNA 512/4885CYP2C19 3931/4885MMP1 489/4885 |
| US-20040058965-A1 | Alkanoic acid derivatives process for their production and use thereof | GPR119, ACOX1, ALK | LMNA 1867/4885CYP2C19 744/4885MMP1 3730/4885 |
| US-20120142717-A1 | COMPOUNDS | LIPG, PLA2G1B, ENPP2 | LMNA 512/4885CYP2C19 3931/4885MMP1 489/4885 |
| US-20130252963-A1 | PYRIMIDINONE COMPOUNDS FOR USE IN THE TREATMENT OF DISEASE OR CONDITIONS MEDIATED BY LP-PLA2 | PLA2G1B, PLA2G4A, PLA2G4B | LMNA 502/4885CYP2C19 2952/4885MMP1 607/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.