SCHEMBL236489

SCHEMBL236489

O=C(O)Oc1ccc(-c2ccc3ccccc3c2)cc1-c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACMSD Q8TDX5 1/20 0.46
GPR84 Q9NQS5 1/20 0.45
HSD17B1 P14061 2/20 0.45
HSD17B2 P37059 2/20 0.45
ESR1 P03372 3/20 0.43
ESR2 Q92731 3/20 0.43
GSTP1 P09211 1/20 0.43
SLC6A2 P23975 1/20 0.43
SLC6A4 P31645 1/20 0.43
SLC6A3 Q01959 1/20 0.43
ACLY P53396 1/20 0.43
SLC6A9 P48067 1/20 0.43
ALOX5 P09917 1/20 0.42
MEN1 O00255 2/20 0.41
MAPT P10636 2/20 0.41
KMT2A Q03164 2/20 0.41
TDP1 Q9NUW8 1/20 0.41
MAPK1 P28482 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
SIRT2 Q8IXJ6 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bicarbonate SCHEMBL28016114 0.98 ACMSD (0.45) ACMSDGPR84HSD17B1HSD17B2ESR1
SCHEMBL17697651 0.89 SLC6A9 (0.51) ACMSDACLYSLC6A9MEN1MAPT
SCHEMBL236487 0.88 ESR1 (0.47) ACMSDHSD17B1HSD17B2ESR1ESR2
Bicarbonate SCHEMBL28016111 0.86 ESR1 (0.46) ACMSDHSD17B1HSD17B2ESR1ESR2
SCHEMBL2286083 0.84 SLC6A2 (0.53) ACMSDGPR84ESR1ESR2GSTP1
SCHEMBL238322 0.81 MCL1 (0.52) ACMSDSLC6A9HDAC8
SCHEMBL22573117 0.80 HDAC4 (0.43) ACMSDHSD17B1HSD17B2ESR1ESR2
Bicarbonate SCHEMBL28016110 0.80 MCL1 (0.51) ACMSDSLC6A9HDAC8
SCHEMBL5873749 0.78 NCEH1 (0.39) GPR84ACLYSLC6A9ALOX5MEN1
SCHEMBL25274668 0.78 ESR1 (0.55) ACMSDHSD17B1HSD17B2ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2593288-B2 APPARATUS AND PROCESS FOR PRODUCING PRODUCTS FROM PIGMENT-CONTAINING POLYMER MIXTURES COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2025-04-16 EP disclosed
US-20210371609-A1 PLASTIC FILMS WITH REDUCED UV ACTIVITY COVESTRO LLC 2021-12-02 US disclosed
EP-3707198-B1 PLASTIC FILMS WITH REDUCED UV ACTIVITY COVESTRO DEUTSCHLAND AG (DE) 2021-10-27 EP disclosed
EP-3707198-A1 PLASTIC FILMS WITH REDUCED UV ACTIVITY Covestro Deutschland AG (DE) 2020-09-16 EP disclosed
EP-3645297-A1 IMPROVED METHOD FOR THE PARTIAL COLOURING OF PLASTIC PARTS Covestro Deutschland AG (DE) 2020-05-06 EP disclosed
EP-3630875-A1 FILMS HAVING A SCRATCH-RESISTANT COATING AS A COVER LAYER AND LAYERED COMPOSITES COMPRISING SUCH FILMS Covestro Deutschland AG (DE) 2020-04-08 EP disclosed
EP-3038747-B1 TRANSESTERIFICATION OF AROMATIC ALCOHOLS USING A HETEROGENEOUS CATALYST SABIC GLOBAL TECHNOLOGIES BV (NL) 2020-04-08 EP disclosed
EP-3383835-B1 A METHOD FOR RECOVERING AN AROMATIC ALCOHOL FROM A MELT POLYMERIZATION, AND A SYSTEM FOR RECOVERING THE SAME SABIC GLOBAL TECHNOLOGIES BV (NL) 2019-07-24 EP disclosed
WO-2019048986-A1 METHOD FOR PRODUCING A POLYCARBONATE ARTICLE SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2019-03-14 WO disclosed
US-10131178-B2 Layered structure and films for ID documents having improved properties for laser engraving COVESTRO DEUTSCHLAND AG (DE) 2018-11-20 US disclosed
CN-101423473-A Method for producing diaryl carbonates and/or alkylaryl carbonates from dialkyl carbonates BAYER MATERIALSCIENCE AG (DE) 2009-05-06 CN disclosed
US-20090076293-A1 PROCESSES FOR PREPARING DIARYL AND/OR ALKYLARYL CARBONATES FROM DIALKYL CARBONATES BAYER MATERIALSCIENCE AG (DE) 2009-03-19 US disclosed
US-20080319156-A1 Process For The Preparation Of Polycarbonate By The Melt Transesterification Process BAYER MATERIALSCIENCE AG (DE) 2008-12-25 US disclosed
US-20080293960-A1 Process For The Preparation Of Diaryl Carbonates Or Arylalkyl Carbonates From Dialkyl Carbonates BAYER MATERIALSCIENCE AG (DE) 2008-11-27 US disclosed
US-7250483-B2 Inhibition of catalytically active impurities in polycarbonate by the melt transesterification process BAYER MATERIALSCIENCE AG (DE) 2007-07-31 US disclosed
CN-1972983-A Method for producing polycarbonate BAYER MATERIALSCIENCE AG (DE) 2007-05-30 CN disclosed
US-7091302-B2 Process for the preparation of polycarbonate BAYER MATERIALSCIENCE AG (DE) 2006-08-15 US disclosed
US-20060004178-A1 Inhibition of catalytically active impurities in polycarbonate by the melt transesterification process COVESTRO DEUTSCHLAND AG (DE) 2006-01-05 US disclosed
CN-1715306-A Inhibiting catalytically active impurities in polycarbonate prepared by melt transesterification process BAYER MATERIALSCIENCE AG (DE) 2006-01-04 CN disclosed
US-20050239995-A1 Process for the preparation of polycarbonate BAYER MATERIALSCIENCE AG 2005-10-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080293960-A1 Process For The Preparation Of Diaryl Carbonates Or Arylalkyl Carbonates From Dialkyl Carbonates HDHD5, ALKBH3, AHR ACMSD 15/4885GPR84 3164/4885HSD17B1 111/4885
US-20090076293-A1 PROCESSES FOR PREPARING DIARYL AND/OR ALKYLARYL CARBONATES FROM DIALKYL CARBONATES DHCR7, ADH1C, AKR1C4 ACMSD 114/4885GPR84 1253/4885HSD17B1 21/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.