Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | BRAF | P15056 | 1/20 | 0.31 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.31 |
| ▸ | RARA | P10276 | 2/20 | 0.31 |
| ▸ | RARB | P10826 | 2/20 | 0.31 |
| ▸ | RARG | P13631 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23654070 | 0.68 | S1PR1 (0.31) | BRAF | |
| SCHEMBL23473667 | 0.68 | TYR (0.39) | — | |
| SCHEMBL20654547 | 0.65 | ICMT (0.35) | IDO1 | |
| SCHEMBL23864401 | 0.65 | CTRC (0.41) | — | |
| SCHEMBL25039667 | 0.65 | CNR2 (0.41) | — | |
| SCHEMBL20008143 | 0.65 | BRAF (0.38) | BRAF | |
| SCHEMBL23654081 | 0.64 | RARA (0.32) | RARARARBRARG | |
| SCHEMBL10490516 | 0.62 | ALDH1A1 (0.40) | — | |
| SCHEMBL31495953 | 0.62 | LIPG (0.40) | CRHR1 | |
| SCHEMBL25270983 | 0.60 | ALDH1A1 (0.51) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3390404-B1 | TRICYCLIC COMPOUNDS AND COMPOSITIONS AS KINASE INHIBITORS | NOVARTIS AG (CH) | 2021-07-21 | — | — | EP | disclosed |