Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.71 |
| ▸ | NPC1 | O15118 | 4/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.71 |
| ▸ | MAPT | P10636 | 4/20 | 0.71 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.71 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.71 |
| ▸ | RELA | Q04206 | 3/20 | 0.71 |
| ▸ | SETD7 | Q8WTS6 | 5/20 | 0.69 |
| ▸ | CISD2 | Q8N5K1 | 7/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25106688 | 0.87 | RAB9A (0.77) | RAB9ANPC1ALDH1A1MAPTNFKB1 | |
| SCHEMBL8290684 | 0.85 | CISD2 (0.83) | RAB9ANPC1ALDH1A1MAPTNFKB1 | |
| SCHEMBL9400304 | 0.84 | RAB9A (1.00) | RAB9ANPC1ALDH1A1MAPTNFKB1 | |
| SCHEMBL13236165 | 0.80 | ALDH1A1 (0.76) | RAB9ANPC1ALDH1A1MAPTNFKB1 | |
| SCHEMBL20838890 | 0.80 | RAB9A (0.69) | RAB9ANPC1ALDH1A1MAPTNFKB1 | |
| SCHEMBL25106697 | 0.79 | CISD2 (0.80) | RAB9ANPC1ALDH1A1MAPTNFKB1 | |
| SCHEMBL248772 | 0.79 | MAPT (0.75) | RAB9ANPC1ALDH1A1MAPTNFKB1 | |
| SCHEMBL25106678 | 0.76 | CISD2 (1.00) | RAB9ANPC1ALDH1A1MAPTNFKB1 | |
| SCHEMBL25106677 | 0.76 | CISD2 (1.00) | RAB9ANPC1ALDH1A1MAPTNFKB1 | |
| SCHEMBL432052 | 0.76 | MAPT (0.59) | RAB9ANPC1ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210220408-A1 | ARYL HYDROCARBON RECEPTOR ANTAGONISTS AND METHODS OF USE | EDIGENE BIOTECHNOLOGY, INC. (CN) | 2021-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210220408-A1 | ARYL HYDROCARBON RECEPTOR ANTAGONISTS AND METHODS OF USE | AHR, ARNT, ARSA | RAB9A 4056/4885NPC1 1022/4885ALDH1A1 98/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.