Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 3/20 | 0.37 |
| ▸ | P2RX2 | Q9UBL9 | 3/20 | 0.37 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.36 |
| ▸ | VNN1 | O95497 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.35 |
| ▸ | CXCR3 | P49682 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2365943 | 1.00 | P2RX3 (0.37) | P2RX3P2RX2SLC6A7VNN1EGLN1 | |
| SCHEMBL2366048 | 0.92 | SLC6A7 (0.37) | SLC6A7EGLN1SMN1; SMN2KDM4ENTSR1 | |
| SCHEMBL2366074 | 0.92 | SLC6A7 (0.37) | SLC6A7EGLN1SMN1; SMN2KDM4ENTSR1 | |
| SCHEMBL2366668 | 0.92 | LMNA (0.35) | SLC6A7EGLN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL2366675 | 0.92 | LMNA (0.35) | SLC6A7EGLN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL2365671 | 0.92 | P2RX3 (0.38) | P2RX3P2RX2SLC6A7VNN1EGLN1 | |
| SCHEMBL2365683 | 0.92 | P2RX3 (0.38) | P2RX3P2RX2SLC6A7VNN1EGLN1 | |
| SCHEMBL2366766 | 0.91 | LMNA (0.37) | SLC6A7EGLN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL2366761 | 0.91 | LMNA (0.37) | SLC6A7EGLN1KMT2ASMN1; SMN2KDM4E | |
| Hydrochloric Acid SCHEMBL2547078 | 0.88 | SLC6A7 (0.37) | SLC6A7EGLN1CXCR3KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2364975-B1 | NOVEL AMIDE DERIVATIVE AND USE THEREOF AS MEDICINE | MITSUBISHI TANABE PHARMA CORP (JP) | 2013-06-12 | — | — | EP | disclosed |
| US-8354401-B2 | Oxazolidinone amide aromatic compounds for supressing MMP-9 production | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2013-01-15 | — | — | US | disclosed |
| US-20110263571-A1 | NOVEL AMIDE DERIVATIVE AND USE THEREOF AS MEDICINE | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2011-10-27 | — | — | US | disclosed |
| EP-2364975-A1 | NOVEL AMIDE DERIVATIVE AND USE THEREOF AS MEDICINE | Mitsubishi Tanabe Pharma Corporation (JP) | 2011-09-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110263571-A1 | NOVEL AMIDE DERIVATIVE AND USE THEREOF AS MEDICINE | MMP9, MMP10, MMP2 | P2RX3 3992/4885P2RX2 3651/4885SLC6A7 992/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.