Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ACP1 | P24666 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30062700 | 1.00 | KIF11 (0.41) | KIF11MAPTHPGDLMNATSHR | |
| SCHEMBL21883075 | 0.83 | MAPT (0.43) | MAPTHPGDLMNATSHRALOX15 | |
| SCHEMBL23037530 | 0.83 | KDM1A (0.47) | MAPTHPGDLMNATSHRTLR7 | |
| SCHEMBL23037505 | 0.82 | MAPT (0.48) | MAPTHPGDLMNATSHRALOX15 | |
| SCHEMBL30060707 | 0.81 | TUBB4A (0.48) | MAPTHPGDLMNATSHRALOX15 | |
| SCHEMBL21883076 | 0.81 | TUBB4A (0.48) | MAPTHPGDLMNATSHRALOX15 | |
| SCHEMBL23668713 | 0.77 | CHKA (0.46) | MAPTHPGDLMNATSHRALOX15 | |
| SCHEMBL30060686 | 0.77 | CHKA (0.46) | MAPTHPGDLMNATSHRALOX15 | |
| SCHEMBL25992599 | 0.77 | MEN1 (0.46) | MAPTHPGDLMNATSHRALOX15 | |
| SCHEMBL3113776 | 0.76 | EGFR (0.53) | MAPTHPGDLMNAACP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12371417-B2 | Compounds with tubulin polymerisation inhibitory activity and immunomodulatory properties | Universite Paris-Saclay (FR) | 2025-07-29 | — | — | US | disclosed |
| US-20230203005-A1 | COMPOUNDS WITH TUBULIN POLYMERISATION INHIBITORY ACTIVITY AND IMMUNOMODULATORY PROPERTIES | Universite Paris-Saclay (FR) | 2023-06-29 | — | — | US | disclosed |
| US-20230203005-A1 | COMPOUNDS WITH TUBULIN POLYMERISATION INHIBITORY ACTIVITY AND IMMUNOMODULATORY PROPERTIES | Universite Paris-Saclay (FR) | 2023-06-29 | — | — | US | disclosed |
| US-20230203005-A1 | COMPOUNDS WITH TUBULIN POLYMERISATION INHIBITORY ACTIVITY AND IMMUNOMODULATORY PROPERTIES | Universite Paris-Saclay (FR) | 2023-06-29 | — | — | US | disclosed |
| US-11634405-B2 | Compounds with tubulin polymerisation inhibitory activity and immunomodulatory properties | UNIVERSITE PARIS-SACLAY PARC TECHNOLOGIQUE (FR) | 2023-04-25 | — | — | US | disclosed |
| US-11634405-B2 | Compounds with tubulin polymerisation inhibitory activity and immunomodulatory properties | UNIVERSITE PARIS-SACLAY PARC TECHNOLOGIQUE (FR) | 2023-04-25 | — | — | US | disclosed |
| US-20210230140-A1 | COMPOUNDS WITH TUBULIN POLYMERISATION INHIBITORY ACTIVITY AND IMMUNOMODULATORY PROPERTIES | Universite Paris-Saclay (FR) | 2021-07-29 | — | — | US | disclosed |
| US-20210230140-A1 | COMPOUNDS WITH TUBULIN POLYMERISATION INHIBITORY ACTIVITY AND IMMUNOMODULATORY PROPERTIES | Universite Paris-Saclay (FR) | 2021-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12371417-B2 | Compounds with tubulin polymerisation inhibitory activity and immunomodulatory properties | TUBB1, TUBB, TUBB3 | KIF11 58/4885MAPT 34/4885HPGD 2890/4885 |
| US-11634405-B2 | Compounds with tubulin polymerisation inhibitory activity and immunomodulatory properties | TUBB1, TUBB, TUBB3 | KIF11 58/4885MAPT 34/4885HPGD 2890/4885 |
| US-20230203005-A1 | COMPOUNDS WITH TUBULIN POLYMERISATION INHIBITORY ACTIVITY AND IMMUNOMODULATORY PROPERTIES | TUBB1, TUBB, TUBB3 | KIF11 58/4885MAPT 34/4885HPGD 2890/4885 |
| US-20210230140-A1 | COMPOUNDS WITH TUBULIN POLYMERISATION INHIBITORY ACTIVITY AND IMMUNOMODULATORY PROPERTIES | TUBB1, TUBB, TUBB3 | KIF11 58/4885MAPT 34/4885HPGD 2890/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.