Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QRFPR | Q96P65 | 1/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.39 |
| ▸ | IL1RN | P18510 | 1/20 | 0.39 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.39 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 3/20 | 0.38 |
| ▸ | CTSS | P25774 | 2/20 | 0.38 |
| ▸ | MBTPS1 | Q14703 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PRKCA | P17252 | 1/20 | 0.37 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 3/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2367341 | 0.92 | ACE (0.45) | ACECTSLCTSSMBTPS1POLB | |
| SCHEMBL2367484 | 0.90 | PSMB8 (0.42) | PSMB5ACECTSLCTSSMBTPS1 | |
| Trifluoroacetic Acid SCHEMBL27766499 | 0.89 | QRFPR (0.44) | QRFPRPSMB5ACECTSLCTSS | |
| SCHEMBL2367824 | 0.88 | CTSK (0.43) | PSMB5CTSLCTSSCTSK | |
| SCHEMBL12294448 | 0.87 | QRFPR (0.46) | QRFPRIL1RNERAP2ERAP1ACE | |
| Trifluoroacetic Acid SCHEMBL27766652 | 0.85 | CTSL (0.48) | QRFPRACECTSLCTSSMBTPS1 | |
| SCHEMBL2367415 | 0.85 | CTSS (0.44) | PSMB5IL1RNERAP2ERAP1CTSL | |
| SCHEMBL2367398 | 0.85 | CTSS (0.44) | PSMB5IL1RNERAP2ERAP1CTSL | |
| SCHEMBL2367512 | 0.85 | CTSL (0.41) | PSMB5IL1RNERAP2ERAP1CTSL | |
| SCHEMBL2367297 | 0.82 | MME (0.35) | QRFPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2007794-B1 | LYSOBACTIN AMIDES | AICURIS GMBH & CO KG (DE) | 2011-09-14 | — | — | EP | disclosed |
| EP-2007794-A1 | LYSOBACTIN AMIDES | AiCuris GmbH & Co. KG (DE) | 2008-12-31 | — | — | EP | disclosed |
| WO-2007118691-A1 | LYSOBACTIN AMIDES | AICURIS GMBH & CO. KG (DE) | 2007-10-25 | — | — | WO | disclosed |