Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 2/20 | 0.45 |
| ▸ | MBTPS1 | Q14703 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | TACR1 | P25103 | 3/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | MME | P08473 | 1/20 | 0.41 |
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.41 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2367014 | 0.92 | QRFPR (0.40) | ACECTSLMBTPS1POLBTACR1 | |
| SCHEMBL2367484 | 0.90 | PSMB8 (0.42) | ACECTSLMBTPS1POLBPTPN1 | |
| SCHEMBL2367824 | 0.88 | CTSK (0.43) | CTSLCTSBCTSSCTSK | |
| Trifluoroacetic Acid SCHEMBL27766652 | 0.87 | CTSL (0.48) | ACECTSLMBTPS1POLBPTPN1 | |
| SCHEMBL2367415 | 0.85 | CTSS (0.44) | CTSLCTSSCTSK | |
| SCHEMBL2367398 | 0.85 | CTSS (0.44) | CTSLCTSSCTSK | |
| SCHEMBL2367196 | 0.85 | CTSC (0.45) | ACECTSLPOLBTACR1CTSB | |
| SCHEMBL12292738 | 0.83 | ACE (0.51) | ACECTSLMBTPS1POLBTACR1 | |
| Trifluoroacetic Acid SCHEMBL27766499 | 0.83 | QRFPR (0.44) | ACECTSLMBTPS1POLBTACR1 | |
| SCHEMBL30516239 | 0.82 | ACE (0.62) | ACEMBTPS1POLBTACR1MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2007794-B1 | LYSOBACTIN AMIDES | AICURIS GMBH & CO KG (DE) | 2011-09-14 | — | — | EP | disclosed |
| EP-2007794-A1 | LYSOBACTIN AMIDES | AiCuris GmbH & Co. KG (DE) | 2008-12-31 | — | — | EP | disclosed |
| WO-2007118691-A1 | LYSOBACTIN AMIDES | AICURIS GMBH & CO. KG (DE) | 2007-10-25 | — | — | WO | disclosed |