Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 3/20 | 0.41 |
| ▸ | CTSS | P25774 | 3/20 | 0.41 |
| ▸ | IL1RN | P18510 | 1/20 | 0.41 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.41 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.41 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 4/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PRKCA | P17252 | 1/20 | 0.37 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2367196 | 0.91 | CTSC (0.45) | CTSLCTSSMMEANPEPCTSK | |
| SCHEMBL2367378 | 0.89 | PSMB1 (0.41) | CTSLCTSSMMEANPEPCTSK | |
| SCHEMBL2367498 | 0.87 | CTSS (0.46) | CTSLCTSSIL1RNERAP2ERAP1 | |
| SCHEMBL2367014 | 0.85 | QRFPR (0.40) | CTSLCTSSIL1RNERAP2ERAP1 | |
| SCHEMBL2367418 | 0.84 | CTSS (0.44) | CTSLCTSSIL1RNERAP2ERAP1 | |
| SCHEMBL2367197 | 0.84 | CTSS (0.44) | CTSLCTSSIL1RNERAP2ERAP1 | |
| SCHEMBL12294438 | 0.84 | ALDH1A1 (0.46) | CTSLIL1RNERAP2ERAP1MME | |
| SCHEMBL10825292 | 0.82 | ALDH1A1 (0.56) | CTSLCTSSMMEANPEPCTSK | |
| SCHEMBL2367341 | 0.81 | ACE (0.45) | CTSLCTSSMMEANPEPCTSK | |
| SCHEMBL2367824 | 0.81 | CTSK (0.43) | CTSLCTSSCTSKPSMB5CTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2007794-B1 | LYSOBACTIN AMIDES | AICURIS GMBH & CO KG (DE) | 2011-09-14 | — | — | EP | disclosed |
| EP-2007794-A1 | LYSOBACTIN AMIDES | AiCuris GmbH & Co. KG (DE) | 2008-12-31 | — | — | EP | disclosed |
| WO-2007118691-A1 | LYSOBACTIN AMIDES | AICURIS GMBH & CO. KG (DE) | 2007-10-25 | — | — | WO | disclosed |