Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 1/20 | 0.42 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.42 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | ECE1 | P42892 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.38 |
| ▸ | PTPRA | P18433 | 1/20 | 0.38 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 2/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | MBTPS1 | Q14703 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2367341 | 0.90 | ACE (0.45) | MMEPTPN1POLBACECTSL | |
| SCHEMBL2367014 | 0.90 | QRFPR (0.40) | PSMB5POLBACECTSLCTSS | |
| SCHEMBL2367824 | 0.86 | CTSK (0.43) | PSMB8PSMB5CTSLCTSS | |
| SCHEMBL2367378 | 0.85 | PSMB1 (0.41) | PSMB8PSMB5PSMB1MMEECE1 | |
| SCHEMBL13723566 | 0.84 | MME (0.44) | PSMB8PSMB5PSMB1MMEECE1 | |
| SCHEMBL2367415 | 0.83 | CTSS (0.44) | PSMB8PSMB5CTSLCTSS | |
| SCHEMBL2367398 | 0.83 | CTSS (0.44) | PSMB8PSMB5CTSLCTSS | |
| SCHEMBL2367498 | 0.80 | CTSS (0.46) | MMECTSLCTSSMEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL27766499 | 0.79 | QRFPR (0.44) | PSMB5POLBACECTSLCTSS | |
| SCHEMBL2367196 | 0.79 | CTSC (0.45) | MMEPOLBACECTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2007794-B1 | LYSOBACTIN AMIDES | AICURIS GMBH & CO KG (DE) | 2011-09-14 | — | — | EP | disclosed |
| EP-2007794-A1 | LYSOBACTIN AMIDES | AiCuris GmbH & Co. KG (DE) | 2008-12-31 | — | — | EP | disclosed |
| WO-2007118691-A1 | LYSOBACTIN AMIDES | AICURIS GMBH & CO. KG (DE) | 2007-10-25 | — | — | WO | disclosed |