Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.44 |
| ▸ | TACR1 | P25103 | 3/20 | 0.44 |
| ▸ | MME | P08473 | 1/20 | 0.44 |
| ▸ | ANPEP | P15144 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.42 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 2/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2367512 | 0.91 | CTSL (0.41) | MMEANPEPCTSLPOLBCTSS | |
| SCHEMBL2367378 | 0.89 | PSMB1 (0.41) | MMEANPEPCTSLPOLBCTSS | |
| SCHEMBL2367498 | 0.87 | CTSS (0.46) | MMEANPEPCTSLCTRB1CTSS | |
| SCHEMBL2367341 | 0.85 | ACE (0.45) | TACR1MMEANPEPCTSLPOLB | |
| SCHEMBL2367197 | 0.84 | CTSS (0.44) | MMEANPEPCTSLCTSSCTSB | |
| SCHEMBL2367418 | 0.84 | CTSS (0.44) | MMEANPEPCTSLCTSSCTSB | |
| SCHEMBL8673841 | 0.84 | TACR1 (0.59) | CTSCOPRK1TACR1MMEANPEP | |
| SCHEMBL28490041 | 0.84 | TACR1 (0.59) | CTSCOPRK1TACR1MMEANPEP | |
| SCHEMBL16984799 | 0.84 | CTSC (0.47) | CTSCOPRK1TACR1MMEANPEP | |
| Trifluoroacetic Acid SCHEMBL10443782 | 0.83 | CTSK (0.54) | CTSLCTSSCTSBCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2007794-B1 | LYSOBACTIN AMIDES | AICURIS GMBH & CO KG (DE) | 2011-09-14 | — | — | EP | disclosed |
| EP-2007794-A1 | LYSOBACTIN AMIDES | AiCuris GmbH & Co. KG (DE) | 2008-12-31 | — | — | EP | disclosed |
| WO-2007118691-A1 | LYSOBACTIN AMIDES | AICURIS GMBH & CO. KG (DE) | 2007-10-25 | — | — | WO | disclosed |