SCHEMBL2368149

SCHEMBL2368149

COCC(O)(Br)OC(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 1/20 0.36
KIF11 P52732 1/20 0.36
ALOX15 P16050 2/20 0.35
ALDH1A1 P00352 2/20 0.35
CHRM3 P20309 2/20 0.35
CYP2C19 P33261 4/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2C9 P11712 1/20 0.34
KMT2A Q03164 2/20 0.34
SMN1; SMN2 Q16637 1/20 0.33
MAPK1 P28482 1/20 0.33
CES1 P23141 1/20 0.33
CYP2D6 P10635 1/20 0.33
HSD17B10 Q99714 1/20 0.33
HIF1A Q16665 1/20 0.32
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
TTR P02766 1/20 0.32
TAAR1 Q96RJ0 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28979286 0.76 ALDH1A1 (0.45) KCNN4ALOX15ALDH1A1CHRM3CYP2C19
SCHEMBL6494684 0.76 KCNN4 (0.41) KCNN4ALOX15ALDH1A1CHRM3CYP2C19
SCHEMBL19884937 0.74 SMN1; SMN2 (0.47) KCNN4ALOX15ALDH1A1CHRM3CYP2C19
SCHEMBL235054 0.73 MAPK1 (0.42) KCNN4KIF11ALOX15ALDH1A1MAPK1
SCHEMBL7066085 0.73 MAPK1 (0.42) KCNN4KIF11ALOX15ALDH1A1MAPK1
SCHEMBL3205224 0.71 ALOX15 (0.43) KCNN4ALOX15ALDH1A1CHRM3CYP2C19
SCHEMBL670716 0.71 CES1 (0.40) KCNN4ALOX15ALDH1A1CHRM3CYP2C19
SCHEMBL22708285 0.71 MAPK1 (0.50) KCNN4KIF11ALOX15ALDH1A1CYP2C19
SCHEMBL8973 0.70 KIF11 (0.48) KCNN4KIF11ALOX15ALDH1A1CYP2C19
SCHEMBL6490060 0.69 CYP2C19 (0.45) KCNN4ALOX15ALDH1A1CHRM3CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8017347-B2 Binder for C-reactive protein MODPRO AB (SE) 2011-09-13 US disclosed
US-20090305298-A1 Binder for C-Reactive Protein MODPRO AB (SE) 2009-12-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090305298-A1 Binder for C-Reactive Protein C1QBP, RBP1, MYCBP KCNN4 4067/4885KIF11 4602/4885ALOX15 3900/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.