Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | IKBKB | O14920 | 1/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.38 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.38 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10493450 | 0.80 | IKBKB (0.43) | ALDH1A1IKBKBTDO2KDM4EMAPT | |
| SCHEMBL2368789 | 0.80 | PTGS2 (0.53) | IKBKBTDO2KDM4EMAPTHPGD | |
| SCHEMBL3423443 | 0.78 | ALDH1A1 (0.44) | ALDH1A1CYP2A6CYP2B6PDE4APDE4B | |
| SCHEMBL5153317 | 0.78 | TDO2 (0.45) | ALDH1A1HSD17B10IKBKBTDO2SMARCA2 | |
| SCHEMBL1982822 | 0.77 | TDO2 (0.50) | ALDH1A1HSD17B10CYP2A6CYP2B6TDO2 | |
| SCHEMBL10205947 | 0.77 | PLA2G10 (0.49) | ALDH1A1CYP2A6CYP2B6ESR2BACE1 | |
| SCHEMBL15652195 | 0.76 | BRD4 (0.42) | ALDH1A1C1SRORCRORB | |
| SCHEMBL11964997 | 0.75 | CYP2A6 (0.41) | ALDH1A1CYP2A6CYP2B6ESR2BACE1 | |
| SCHEMBL8071081 | 0.75 | ALDH1A1 (0.38) | ALDH1A1HSD17B10PDE4APDE4BPDE4C | |
| SCHEMBL2616385 | 0.72 | CYP2A6 (0.38) | HSD17B10CYP2A6CYP2B6ESR2BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8022076-B2 | Thieno[2,3-d]pyrimidine derivatives as potassium channel modulators; antiarrhythmia agents | XENTION LIMITED (GB) | 2011-09-20 | — | — | US | disclosed |
| US-20090048258-A1 | Amide Compound | TAKEDA, PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-02-19 | — | — | US | disclosed |
| US-20050026935-A1 | Compounds | XENTION DISCOVERY LTD. | 2005-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050026935-A1 | Compounds | KCNJ11, KCNJ1, KCNH1 | ALDH1A1 247/4885HSD17B10 905/4885CYP2A6 391/4885 |
| US-20090048258-A1 | Amide Compound | DLAT, DGAT1, DGAT2 | ALDH1A1 435/4885HSD17B10 313/4885CYP2A6 2105/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.