SCHEMBL2369739

SCHEMBL2369739

CCCCN(C(=O)CCCCCCCCC(=O)N(CCCC)C1CC(C)(C)N(OCC)C(C)(C)C1)C1CC(C)(C)N(OCC)C(C)(C)C1

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KDM5A P29375 9/20 0.33
KDM4C Q9H3R0 8/20 0.33
PHF8 Q9UPP1 4/20 0.33
KDM4A O75164 2/20 0.33
CNR2 P34972 1/20 0.32
SRD5A1 P18405 2/20 0.31
EPHX2 P34913 1/20 0.31
SRD5A2 P31213 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14690418 0.90 KDM5A (0.33) KDM5AKDM4CPHF8KDM4ACNR2
SCHEMBL2455260 0.84 EPHX2 (0.35) CNR2EPHX2ALDH1A1
SCHEMBL272291 0.84 KDM4C (0.37) KDM5AKDM4CPHF8KDM4ACNR2
SCHEMBL272810 0.84 KDM4C (0.37) KDM5AKDM4CPHF8KDM4ACNR2
SCHEMBL14690061 0.84 L3MBTL1 (0.32) SRD5A1L3MBTL1
SCHEMBL14702025 0.81 ALDH1A1 (0.33) EPHX2ALDH1A1
SCHEMBL9378729 0.79 L3MBTL1 (0.31) SRD5A1L3MBTL1
SCHEMBL9351981 0.76 EPHX2 (0.36) CNR2EPHX2
SCHEMBL16939131 0.76 PDE3B (0.31) ALDH1A1
SCHEMBL2462031 0.76 DGKA (0.34) CNR2EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150210828-A1 STERICALLY HINDERED AMINES BASF SE (DE) 2015-07-30 US disclosed
US-9045430-B2 Sterically hindered amines BASF SE (DE) 2015-06-02 US disclosed
EP-2542526-B1 Sterically hindered amines BASF SE (DE) 2015-05-13 EP disclosed
US-20130041076-A1 STERICALLY HINDERED AMINES BASF SE (DE) 2013-02-14 US disclosed
EP-2542526-A1 STERICALLY HINDERED AMINES BASF SE (DE) 2013-01-09 EP disclosed
WO-2011107513-A1 STERICALLY HINDERED AMINES BASF SE (DE) 2011-09-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150210828-A1 STERICALLY HINDERED AMINES CCNA1, C5, H1-0 KDM5A 942/4885KDM4C 1217/4885PHF8 1088/4885
US-20130041076-A1 STERICALLY HINDERED AMINES CCNA1, C5, H1-0 KDM5A 942/4885KDM4C 1217/4885PHF8 1088/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.