Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 6/20 | 0.37 |
| ▸ | KDM5A | P29375 | 5/20 | 0.37 |
| ▸ | PHF8 | Q9UPP1 | 4/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.35 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.34 |
| ▸ | KDM4A | O75164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 3/20 | 0.33 |
| ▸ | CES1 | P23141 | 3/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL272291 | 1.00 | KDM4C (0.37) | KDM4CKDM5APHF8EPHX2SRD5A1 | |
| SCHEMBL2369739 | 0.84 | KDM5A (0.33) | KDM4CKDM5APHF8EPHX2SRD5A1 | |
| SCHEMBL14690418 | 0.84 | KDM5A (0.33) | KDM4CKDM5APHF8EPHX2SRD5A1 | |
| SCHEMBL4960134 | 0.82 | ALDH1A1 (0.37) | SRD5A1ALDH1A1ALOX15 | |
| SCHEMBL308455 | 0.82 | SRD5A1 (0.38) | SRD5A1ALDH1A1ALOX15 | |
| SCHEMBL8430751 | 0.79 | KDM5A (0.38) | KDM4CKDM5APHF8EPHX2SRD5A1 | |
| SCHEMBL536568 | 0.78 | KDM5A (0.35) | KDM4CKDM5APHF8EPHX2SRD5A1 | |
| SCHEMBL14690061 | 0.78 | L3MBTL1 (0.32) | SRD5A1 | |
| SCHEMBL11059443 | 0.77 | EPHX2 (0.37) | KDM4CKDM5APHF8EPHX2ALDH1A1 | |
| SCHEMBL8850280 | 0.77 | GNAI3 (0.39) | KDM4CKDM5APHF8ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8134009-B2 | Process for the oxidation of secondary amines into the corresponding nitroxides | BASF SE (DE) | 2012-03-13 | — | — | US | disclosed |
| US-20100305322-A1 | Process for the Oxidation of Secondary Amines into the Corresponding Nitroxides | CIBA SPECIALTY CHEMICALS CORPORATION | 2010-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100305322-A1 | Process for the Oxidation of Secondary Amines into the Corresponding Nitroxides | NOS2, NOS1, NOS3 | KDM4C 1687/4885KDM5A 659/4885PHF8 344/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.