Sugi Predict

Sugi Predict / Compounds / SCHEMBL2455260

SCHEMBL2455260

SCHEMBL2455260

CCCCCCCCCCCCCCCCCC(=O)N(C1CC(C)(C)N(OCC)C(C)(C)C1)C1CC(C)(C)N(OCC)C(C)(C)C1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ EPHX2 P34913 2/20 0.35
▸ CNR2 P34972 1/20 0.35
▸ NAAA Q02083 2/20 0.34
▸ CES2 O00748 3/20 0.33
▸ CES1 P23141 3/20 0.33
▸ DGKA P23743 1/20 0.33
▸ PPARG P37231 4/20 0.33
▸ PPARD Q03181 4/20 0.33
▸ PPARA Q07869 4/20 0.33
▸ TSHR P16473 3/20 0.33
▸ GPR84 Q9NQS5 3/20 0.33
▸ HDAC11 Q96DB2 3/20 0.33
▸ ALDH1A1 P00352 2/20 0.33
▸ TDP1 Q9NUW8 2/20 0.33
▸ SLC22A6 Q4U2R8 1/20 0.33
▸ SLC22A8 Q8TCC7 1/20 0.33
▸ TLR2 O60603 1/20 0.33
▸ MEN1 O00255 1/20 0.33
▸ ESR1 P03372 1/20 0.33
▸ FABP4 P15090 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2462031 0.92 DGKA (0.34) EPHX2CNR2NAAACES2CES1
SCHEMBL9351981 0.92 EPHX2 (0.36) EPHX2CNR2NAAADGKA
SCHEMBL2457690 0.89 EPHX2 (0.33) EPHX2CNR2
SCHEMBL2369739 0.84 KDM5A (0.33) EPHX2CNR2ALDH1A1
SCHEMBL14702025 0.83 ALDH1A1 (0.33) EPHX2ALDH1A1ALOX15PDE4APDE3A
SCHEMBL9351971 0.79 EPHX2 (0.35) EPHX2NAAACES2TSHR
SCHEMBL16939131 0.78 PDE3B (0.31) ALDH1A1ALOX15PDE4APDE3A
SCHEMBL9350803 0.76 NAAA (0.38) NAAAPDE3A
SCHEMBL9352000 0.74 EPHX2 (0.40) EPHX2
SCHEMBL14690418 0.73 KDM5A (0.33) EPHX2CNR2ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11161813-B2 Sterically hindered amines BASF SE (DE) 2021-11-02 — — US disclosed
US-20200123107-A1 STERICALLY HINDERED AMINES BASF SE (DE) 2020-04-23 — — US disclosed
US-20180319746-A1 STERICALLY HINDERED AMINES BASF SE (DE) 2018-11-08 — — US disclosed
US-10040762-B2 Sterically hindered amines BASF SE (DE) 2018-08-07 — — US disclosed
EP-2545035-B1 STERICALLY HINDERED AMINES BASF SE (DE) 2017-08-09 — — EP disclosed
US-20130053484-A1 STERICALLY HINDERED AMINES BASF SE (DE) 2013-02-28 — — US disclosed
EP-2545035-A2 STERICALLY HINDERED AMINES BASF SE (DE) 2013-01-16 — — EP disclosed
WO-2011107515-A2 STERICALLY HINDERED AMINES BASF SE (DE) 2011-09-09 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11161813-B2 Sterically hindered amines H1-0, F12, H1-2 EPHX2 652/4885CNR2 917/4885NAAA 1141/4885
US-20180319746-A1 STERICALLY HINDERED AMINES H1-0, F12, H1-2 EPHX2 652/4885CNR2 917/4885NAAA 1141/4885
US-20200123107-A1 STERICALLY HINDERED AMINES H1-0, F12, H1-2 EPHX2 652/4885CNR2 917/4885NAAA 1141/4885
US-10040762-B2 Sterically hindered amines H1-0, F12, H1-2 EPHX2 652/4885CNR2 917/4885NAAA 1141/4885
US-20130053484-A1 STERICALLY HINDERED AMINES H1-0, F12, H1-2 EPHX2 652/4885CNR2 917/4885NAAA 1141/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.