Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 3/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.41 |
| ▸ | CTSG | P08311 | 2/20 | 0.41 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.41 |
| ▸ | CMA1 | P23946 | 2/20 | 0.41 |
| ▸ | MMP2 | P08253 | 2/20 | 0.41 |
| ▸ | MMP3 | P08254 | 2/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23719091 | 1.00 | CTSK (0.44) | CTSKCTSSACEGRIK1HTR2C | |
| SCHEMBL23699429 | 0.88 | CYP1A2 (0.51) | ACEHTR2CSLC6A4 | |
| SCHEMBL23699444 | 0.80 | FOLH1 (0.50) | HTR2CSLC6A4PTGESALOX5PPARG | |
| SCHEMBL7458715 | 0.80 | MLYCD (0.50) | CTSKHTR2CSLC6A4 | |
| SCHEMBL28559718 | 0.79 | NPC1 (0.54) | ACEGRIK1 | |
| SCHEMBL1915090 | 0.79 | CTSS (0.46) | CTSKCTSSGRIK1PRSS1CTSG | |
| SCHEMBL1914954 | 0.79 | CTSS (0.46) | CTSKCTSSGRIK1PRSS1CTSG | |
| SCHEMBL1914958 | 0.79 | CTSS (0.46) | CTSKCTSSGRIK1PRSS1CTSG | |
| SCHEMBL17826809 | 0.78 | CHRNB2 (0.40) | CTSKCTSS | |
| SCHEMBL23699386 | 0.78 | CTSS (0.47) | CTSKCTSSHTR2CSLC6A4PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3858439-A1 | AMIDE DERIVATIVES HAVING MULTIMODAL ACTIVITY AGAINST PAIN | ESTEVE PHARMACEUTICALS, S.A. (ES) | 2021-08-04 | — | — | EP | disclosed |
| EP-3858439-A1 | AMIDE DERIVATIVES HAVING MULTIMODAL ACTIVITY AGAINST PAIN | ESTEVE PHARMACEUTICALS, S.A. (ES) | 2021-08-04 | — | — | EP | disclosed |