Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 9/20 | 0.38 |
| ▸ | CTSK | P43235 | 7/20 | 0.38 |
| ▸ | CTSL | P07711 | 2/20 | 0.37 |
| ▸ | CTSB | P07858 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 2/20 | 0.34 |
| ▸ | FAP | Q12884 | 1/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23699386 | 0.82 | CTSS (0.47) | PTPN1CTSSCTSKSLC6A4 | |
| SCHEMBL1915404 | 0.82 | PTPN1 (0.40) | MAOBPTPN1CTSSCTSKCTSL | |
| SCHEMBL1915409 | 0.82 | PTPN1 (0.40) | MAOBPTPN1CTSSCTSKCTSL | |
| SCHEMBL23699429 | 0.81 | CYP1A2 (0.51) | SLC6A4 | |
| SCHEMBL25182312 | 0.81 | MAOB (0.42) | MAOBPTPN1CTSSCTSKCTSL | |
| SCHEMBL23699431 | 0.80 | MAOB (0.42) | MAOBPTPN1CTSSCTSKCTSL | |
| SCHEMBL23699440 | 0.79 | FOLH1 (0.56) | MAOBCTSSCTSKCTSLCTSB | |
| SCHEMBL7382769 | 0.78 | CYP1A2 (0.50) | MAOBSLC6A2SLC6A4FFAR1DPP4 | |
| SCHEMBL23719091 | 0.75 | CTSK (0.44) | CTSSCTSKSLC6A4 | |
| SCHEMBL23699255 | 0.75 | CTSK (0.44) | CTSSCTSKSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3858439-A1 | AMIDE DERIVATIVES HAVING MULTIMODAL ACTIVITY AGAINST PAIN | ESTEVE PHARMACEUTICALS, S.A. (ES) | 2021-08-04 | — | — | EP | disclosed |
| EP-3858439-A1 | AMIDE DERIVATIVES HAVING MULTIMODAL ACTIVITY AGAINST PAIN | ESTEVE PHARMACEUTICALS, S.A. (ES) | 2021-08-04 | — | — | EP | disclosed |