Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2370088 | 1.00 | LMNA (0.40) | LMNATHRBCA2 | |
| SCHEMBL1542042 | 0.97 | LMNA (0.35) | LMNA | |
| SCHEMBL2370655 | 0.86 | LMNA (0.30) | LMNA | |
| SCHEMBL7617703 | 0.85 | — | — | |
| SCHEMBL15546686 | 0.80 | LMNA (0.40) | LMNATHRBCA2 | |
| SCHEMBL20548486 | 0.76 | LMNA (0.35) | LMNA | |
| SCHEMBL3270860 | 0.76 | LMNA (0.35) | LMNA | |
| Perflexane SCHEMBL7507426 | 0.73 | LMNA (0.61) | LMNATHRBCA2 | |
| SCHEMBL1779065 | 0.73 | LMNA (0.61) | LMNATHRBCA2 | |
| Perflexane SCHEMBL20769778 | 0.73 | LMNA (0.61) | LMNATHRBCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9346838-B2 | Process for the preparation of tris(perfluoroalkyl)phosphine oxides and bis(perfluoroalkyl)phosphinic acids | MERCK PATENT GMBH (DE) | 2016-05-24 | — | — | US | claimed |
| US-20150141698-A1 | PROCESS FOR THE PREPARATION OF TRIS(PERFLUOROALKYL)PHOSPHINE OXIDES AND BIS(PERFLUOROALKYL)PHOSPHINIC ACIDS | MERCK PATENT GMBH (DE) | 2015-05-21 | — | — | US | claimed |
| EP-2867242-A1 | METHOD FOR PRODUCING TRIS (PERFLUOROALKYL) PHOSPHINE OXIDES AND BIS (PERFLUOROALKYL) PHOSPHINIC ACIDS | Merck Patent GmbH (DE) | 2015-05-06 | — | — | EP | claimed |
| US-8962892-B2 | Process for the preparation of tris(perfluoroalkyl)phosphine oxides | MERCK PATENT GMBH (DE) | 2015-02-24 | — | — | US | claimed |
| WO-2014005668-A1 | METHOD FOR PRODUCING TRIS (PERFLUOROALKYL) PHOSPHINE OXIDES AND BIS (PERFLUOROALKYL) PHOSPHINIC ACIDS | MERCK PATENT GMBH (DE) | 2014-01-09 | — | — | WO | claimed |
| US-9346838-B2 | Process for the preparation of tris(perfluoroalkyl)phosphine oxides and bis(perfluoroalkyl)phosphinic acids | MERCK PATENT GMBH (DE) | 2016-05-24 | — | — | US | disclosed |
| US-20150141698-A1 | PROCESS FOR THE PREPARATION OF TRIS(PERFLUOROALKYL)PHOSPHINE OXIDES AND BIS(PERFLUOROALKYL)PHOSPHINIC ACIDS | MERCK PATENT GMBH (DE) | 2015-05-21 | — | — | US | disclosed |
| EP-2867242-A1 | METHOD FOR PRODUCING TRIS (PERFLUOROALKYL) PHOSPHINE OXIDES AND BIS (PERFLUOROALKYL) PHOSPHINIC ACIDS | Merck Patent GmbH (DE) | 2015-05-06 | — | — | EP | disclosed |
| US-8962892-B2 | Process for the preparation of tris(perfluoroalkyl)phosphine oxides | MERCK PATENT GMBH (DE) | 2015-02-24 | — | — | US | disclosed |
| EP-2545062-B1 | PROCESS FOR PREPARING TRIS(PERFLUOROALKYL)PHOSPHINE OXIDES | MERCK PATENT GMBH (DE) | 2014-03-26 | — | — | EP | disclosed |
| WO-2014005668-A1 | METHOD FOR PRODUCING TRIS (PERFLUOROALKYL) PHOSPHINE OXIDES AND BIS (PERFLUOROALKYL) PHOSPHINIC ACIDS | MERCK PATENT GMBH (DE) | 2014-01-09 | — | — | WO | disclosed |
| EP-2545062-A1 | PROCESS FOR PREPARING TRIS(PERFLUOROALKYL)PHOSPHINE OXIDES | Merck Patent GmbH (DE) | 2013-01-16 | — | — | EP | disclosed |
| US-20120330063-A1 | PROCESS FOR THE PREPARATION OF TRIS(PERFLUOROALKYL)PHOSPHINE OXIDES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-12-27 | — | — | US | disclosed |
| WO-2011110281-A1 | PROCESS FOR PREPARING TRIS(PERFLUOROALKYL)PHOSPHINE OXIDES | MERCK PATENT GMBH (DE) | 2011-09-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150141698-A1 | PROCESS FOR THE PREPARATION OF TRIS(PERFLUOROALKYL)PHOSPHINE OXIDES AND BIS(PERFLUOROALKYL)PHOSPHINIC ACIDS | PHOSPHO1, PFKFB4, PFKFB1 | LMNA 3912/4885THRB 532/4885CA2 269/4885 |
| US-20120330063-A1 | PROCESS FOR THE PREPARATION OF TRIS(PERFLUOROALKYL)PHOSPHINE OXIDES | PHOSPHO1, PFAS, CDIPT | LMNA 3815/4885THRB 651/4885CA2 70/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.