Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15546686 | 0.97 | LMNA (0.40) | LMNA | |
| SCHEMBL15546171 | 0.89 | LMNA (0.30) | LMNA | |
| SCHEMBL20548486 | 0.79 | LMNA (0.35) | LMNA | |
| SCHEMBL1542042 | 0.79 | LMNA (0.35) | LMNA | |
| SCHEMBL2369959 | 0.76 | LMNA (0.40) | LMNA | |
| SCHEMBL2370088 | 0.76 | LMNA (0.40) | LMNA | |
| SCHEMBL4020054 | 0.72 | — | — | |
| Perflubutane SCHEMBL9051673 | 0.71 | LMNA (0.54) | LMNA | |
| Perflubutane SCHEMBL111514 | 0.71 | LMNA (0.54) | LMNA | |
| SCHEMBL2370655 | 0.67 | LMNA (0.30) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9346838-B2 | Process for the preparation of tris(perfluoroalkyl)phosphine oxides and bis(perfluoroalkyl)phosphinic acids | MERCK PATENT GMBH (DE) | 2016-05-24 | — | — | US | claimed |
| US-20150141698-A1 | PROCESS FOR THE PREPARATION OF TRIS(PERFLUOROALKYL)PHOSPHINE OXIDES AND BIS(PERFLUOROALKYL)PHOSPHINIC ACIDS | MERCK PATENT GMBH (DE) | 2015-05-21 | — | — | US | claimed |
| EP-1495035-B1 | METHOD FOR THE PRODUCTION OF BIS(PERFLUOROALKYL)PHOSPHINIC ACIDS AND THE SALTS THEREOF | MERCK PATENT GMBH (DE) | 2010-06-30 | — | — | EP | claimed |
| US-7632969-B2 | Process for the preparation of perfluoroalkylphosphines and the use thereof as perfluoroalkylating reagents | MERCK PATENT GMBH (DE) | 2009-12-15 | — | — | US | claimed |
| EP-1495036-B1 | METHOD FOR THE PRODUCTION OF MONOHYDRO-PERFLUOROALKANES, BIS(PERFLUOROALKYL)PHOSPHINATES, AND PERFLUOROALKYLPHOSPHONATES | MERCK PATENT GMBH (DE) | 2009-08-19 | — | — | EP | claimed |
| EP-1495037-B1 | METHOD FOR THE PRODUCTION OF PERFLUOROALKYL PHOSPHINES AND THE USE THEREOF AS PERFLUOROALKYLATING REACTANTS | MERCK PATENT GMBH (DE) | 2009-02-25 | — | — | EP | claimed |
| US-20070191637-A1 | Reacting a (perfluoroalkyl)phosphorane fluoride with a hydride ion donor such as triethylsilane, tripropylsilane or sodium borohydride while refluxing | WELZ-BIERMANN URS | 2007-08-16 | — | — | US | claimed |
| US-7208626-B2 | Method for the production of perfluoroalkyl phosphines and the use thereof as perfluoroalkylating reactants | MERCK PATENT GESELLSCHAFT (DE) | 2007-04-24 | — | — | US | claimed |
| US-7202379-B2 | Process for the preparation of bis(perfluoroalkyl)phosphinic acids and salts thereof | MERCK PATENT GMBH (DE) | 2007-04-10 | — | — | US | claimed |
| US-7145004-B2 | Method for the production of monohydro-perfluoroalkanes, bis(perfluoroalkyl)phosphinates and perfluoroalkylphosphonates | MERCK PATENT GESELLSCHAFT (DE) | 2006-12-05 | — | — | US | claimed |
| US-20050256334-A1 | Process for the preparation of bis(perfluoroalkyl)phosphinic acids and salts thereof | MERCK PATENT GMBH (DE) | 2005-11-17 | — | — | US | claimed |
| US-20050222411-A1 | Method for the production of monohydro-perfluoroalkanes, bis (perfluoroalkyl) phosphinates and perfluoroalkylphosphonates | MERCK PATENT GMBH (DE) | 2005-10-06 | — | — | US | claimed |
| US-20050131256-A1 | Method for the production of perfluoroaldyl phosphines and the use thereof as perfluoroalkylating reactants | MERCK PATENT GMBH (DE) | 2005-06-16 | — | — | US | claimed |
| EP-3398975-B1 | PHOTOSENSITIVE COMPOSITION | SAN APRO LTD (JP) | 2023-02-01 | — | — | EP | disclosed |
| US-20180373145-A1 | PHOTOSENSITIVE COMPOSITION | SAN-APRO LTD. (JP) | 2018-12-27 | — | — | US | disclosed |
| EP-3398975-A1 | PHOTOSENSITIVE COMPOSITION | San-Apro Limited (JP) | 2018-11-07 | — | — | EP | disclosed |
| EP-1399453-B1 | NOVEL STRONG ACIDS, PRODUCTION METHOD AND USES THEREOF | MERCK PATENT GMBH (DE) | 2005-03-02 | — | — | EP | disclosed |
| US-20040171879-A1 | FLUORINATED PHOSPHOROUS ACID, AND SALT THEREOF | MERCK PATENT GMBH (DE) | 2004-09-02 | — | — | US | disclosed |
| EP-1399453-A1 | NOVEL STRONG ACIDS, PRODUCTION METHOD AND USES THEREOF | MERCK PATENT GmbH (DE) | 2004-03-24 | — | — | EP | disclosed |
| WO-2003002579-A1 | NOVEL STRONG ACIDS, PRODUCTION METHOD AND USES THEREOF | MERCK PATENT GMBH (DE) | 2003-01-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150141698-A1 | PROCESS FOR THE PREPARATION OF TRIS(PERFLUOROALKYL)PHOSPHINE OXIDES AND BIS(PERFLUOROALKYL)PHOSPHINIC ACIDS | PHOSPHO1, PFKFB4, PFKFB1 | LMNA 3912/4885 |
| US-20050222411-A1 | Method for the production of monohydro-perfluoroalkanes, bis (perfluoroalkyl) phosphinates and perfluoroalkylphosphonates | PFAS, PFKFB2, PHOSPHO1 | LMNA 1964/4885 |
| US-20050256334-A1 | Process for the preparation of bis(perfluoroalkyl)phosphinic acids and salts thereof | PFAS, PFKFB1, PFKFB4 | LMNA 3301/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.