Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | DCUN1D1 | Q96GG9 | 9/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | UBE2M | P61081 | 8/20 | 0.46 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | GCGR | P47871 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9256017 | 0.81 | ALDH1A1 (0.66) | ALDH1A1TP53ATMLMNADCUN1D1 | |
| Pencycuron SCHEMBL8817027 | 0.80 | AGER (0.62) | ALDH1A1TP53ATMLMNADCUN1D1 | |
| SCHEMBL11615939 | 0.80 | ALDH1A1 (0.61) | ALDH1A1TP53ATMLMNADCUN1D1 | |
| SCHEMBL23199925 | 0.80 | ALDH1A1 (0.65) | ALDH1A1TP53ATMLMNADCUN1D1 | |
| Pencycuron SCHEMBL22525 | 0.80 | AGER (0.62) | ALDH1A1TP53ATMLMNADCUN1D1 | |
| SCHEMBL11057174 | 0.80 | AGER (0.62) | ALDH1A1TP53ATMDCUN1D1UBE2M | |
| SCHEMBL23699893 | 0.79 | ALDH1A1 (0.63) | ALDH1A1TP53ATMLMNADCUN1D1 | |
| SCHEMBL11621624 | 0.79 | AGER (0.64) | ALDH1A1TP53ATMLMNADCUN1D1 | |
| SCHEMBL10337815 | 0.78 | DCUN1D1 (0.63) | ALDH1A1DCUN1D1UBE2MGCGR | |
| SCHEMBL7802288 | 0.78 | DCUN1D1 (0.66) | ALDH1A1DCUN1D1UBE2M |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210238139-A1 | MODULATORS OF TRYPTOPHAN CATABOLISM | E-THERAPEUTICS PLC (GB) | 2021-08-05 | — | — | US | claimed |
| US-20210238139-A1 | MODULATORS OF TRYPTOPHAN CATABOLISM | E-THERAPEUTICS PLC (GB) | 2021-08-05 | — | — | US | disclosed |
| US-20210238139-A1 | MODULATORS OF TRYPTOPHAN CATABOLISM | E-THERAPEUTICS PLC (GB) | 2021-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210238139-A1 | MODULATORS OF TRYPTOPHAN CATABOLISM | TPH1, KYNU, TPH2 | ALDH1A1 606/4885TP53 557/4885ATM 3204/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.