Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.36 |
| ▸ | MET | P08581 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL286638 | 0.77 | LMNA (0.54) | LMNATNKS2NPC1RECQLRAB9A | |
| SCHEMBL7658771 | 0.74 | LMNA (0.69) | LMNACTDSP1KDM4EAPOBEC3AAPOBEC3G | |
| SCHEMBL439039 | 0.74 | DGKA (0.50) | — | |
| SCHEMBL3692999 | 0.73 | LMNA (0.66) | LMNACYP4F2CYP4A11AKR1B10AKR1B1 | |
| SCHEMBL16245538 | 0.73 | LMNA (0.71) | LMNAGAAALDH1A1MAPTNPC1 | |
| SCHEMBL27603021 | 0.73 | LMNA (0.71) | LMNAMETKDM4EALDH1A1AKR1B10 | |
| SCHEMBL669629 | 0.71 | LMNA (0.59) | LMNATNKS2ALDH1A1NPC1RAB9A | |
| SCHEMBL28480435 | 0.71 | LMNA (0.68) | LMNACYP4F2CYP4A11ALDH1A1AKR1B10 | |
| Phenprobamate SCHEMBL134496 | 0.71 | LMNA (1.00) | LMNACTDSP1KDM4EAPOBEC3AAPOBEC3G | |
| SCHEMBL28673196 | 0.70 | LMNA (0.60) | LMNAEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2547667-A1 | PROCESS FOR THE PRODUCTION OF 2-AMINO-5-FLUOROTHIAZOLE | Takeda California, Inc. (US) | 2013-01-23 | — | — | EP | disclosed |
| WO-2011115758-A1 | PROCESS FOR THE PRODUCTION OF 2-AMINO-5-FLUOROTHIAZOLE | TAKEDA SAN DIEGO, INC. (US) | 2011-09-22 | — | — | WO | disclosed |