SCHEMBL23701266

SCHEMBL23701266

CCOC(F)c1ccccc1[SiH3]

nearest known ligand 0.34

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.34
LTA4H P09960 1/20 0.34
L3MBTL1 Q9Y468 5/20 0.34
GLA P06280 1/20 0.34
NQO1 P15559 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C19 P33261 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
PTPRC P08575 1/20 0.33
CDC25B P30305 1/20 0.33
RELA Q04206 1/20 0.32
MAPT P10636 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
TSHR P16473 1/20 0.31
MPO P05164 1/20 0.30
ALOX15 P16050 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL699772 0.82 ALDH1A1 (0.38) ALDH1A1LTA4HL3MBTL1GLANQO1
SCHEMBL14956637 0.78 TSHR (0.35) ALDH1A1LTA4HL3MBTL1GLANQO1
SCHEMBL6551729 0.71 L3MBTL1 (0.42) L3MBTL1CYP1A2CYP2D6NPSR1TSHR
SCHEMBL28598232 0.70 GABRA1 (0.36) CYP1A2TSHR
SCHEMBL3406061 0.69 TRPA1 (0.30)
SCHEMBL3316317 0.69 TSHR (0.40) ALDH1A1LTA4HL3MBTL1GLAMAPT
SCHEMBL15915010 0.67 TSHR (0.59) ALDH1A1L3MBTL1TSHR
SCHEMBL10342114 0.66 ALDH1A1 (0.58) ALDH1A1L3MBTL1GLACYP1A2CYP2D6
SCHEMBL451129 0.66 ESR1 (0.34) ALDH1A1CYP1A2CYP2D6CYP2C19TDP1
SCHEMBL10717115 0.65 TSHR (0.38) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11807758-B2 Siloxane polymer and method of producing siloxane polymer JNC CORPORATION (JP) 2023-11-07 US disclosed
US-20210238419-A1 SILOXANE POLYMER AND METHOD OF PRODUCING SILOXANE POLYMER JNC CORPORATION (JP) 2021-08-05 US disclosed