Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 13/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 13/20 | 0.54 |
| ▸ | MBTD1 | Q05BQ5 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TP53BP1 | Q12888 | 4/20 | 0.43 |
| ▸ | PLK1 | P53350 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.42 |
| ▸ | INSR | P06213 | 1/20 | 0.42 |
| ▸ | IGF1R | P08069 | 1/20 | 0.42 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13165353 | 0.90 | INSR (0.48) | ALDH1A1PLK1INSRIGF1RALK | |
| SCHEMBL12139661 | 0.85 | L3MBTL3 (0.49) | L3MBTL3L3MBTL1MBTD1TP53BP1L3MBTL4 | |
| SCHEMBL23997023 | 0.83 | ALDH1A1 (0.53) | ALDH1A1LMNA | |
| SCHEMBL1911895 | 0.82 | L3MBTL3 (0.58) | L3MBTL3L3MBTL1MBTD1ALDH1A1TP53BP1 | |
| SCHEMBL12139624 | 0.82 | DPP4 (0.43) | ALDH1A1LMNAALKEGFR | |
| SCHEMBL23707075 | 0.82 | NTSR1 (0.42) | ALDH1A1PLK1LMNAINSRIGF1R | |
| SCHEMBL1911852 | 0.81 | L3MBTL3 (0.57) | L3MBTL3L3MBTL1MBTD1ALDH1A1TP53BP1 | |
| SCHEMBL520836 | 0.81 | L3MBTL1 (0.57) | L3MBTL3L3MBTL1MBTD1ALDH1A1TP53BP1 | |
| SCHEMBL23328575 | 0.80 | SUV39H2 (0.43) | ALDH1A1PLK1INSRIGF1RALK | |
| SCHEMBL13981638 | 0.80 | L3MBTL1 (0.55) | L3MBTL3L3MBTL1MBTD1ALDH1A1TP53BP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11078213-B2 | Thienopyrimidine compound, preparation method thereof, pharmaceutical composition and application thereof | Hongyun Biotech Co., Ltd. (CN) | 2021-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11078213-B2 | Thienopyrimidine compound, preparation method thereof, pharmaceutical composition and application thereof | ALK, MET, TIE1 | L3MBTL3 1968/4885L3MBTL1 1569/4885MBTD1 1315/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.