Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 9/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.37 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23704137 | 0.89 | P2RX3 (0.47) | NAMPTMAPTMAPK1ALDH1A1KDM4E | |
| SCHEMBL23704132 | 0.87 | UCHL1 (0.44) | NAMPTMAPTMAPK1P2RX3P2RX2 | |
| SCHEMBL23707316 | 0.84 | MAPK1 (0.40) | NAMPTMAPTMAPK1ALDH1A1KDM4E | |
| SCHEMBL29994149 | 0.84 | MAPK1 (0.40) | NAMPTMAPTMAPK1ALDH1A1KDM4E | |
| SCHEMBL23707375 | 0.83 | MAPK1 (0.36) | NAMPTMAPTMAPK1MEN1ALDH1A1 | |
| SCHEMBL23704277 | 0.82 | MAPT (0.43) | MAPTMEN1ALDH1A1KMT2AKDM4E | |
| SCHEMBL23704107 | 0.81 | ALDH1A1 (0.37) | NAMPTMAPTMAPK1MEN1ALDH1A1 | |
| SCHEMBL29994016 | 0.81 | ALDH1A1 (0.37) | NAMPTMAPTMAPK1MEN1ALDH1A1 | |
| SCHEMBL23704194 | 0.81 | NAMPT (0.37) | NAMPTMAPTMAPK1MEN1ALDH1A1 | |
| SCHEMBL29994245 | 0.81 | NAMPT (0.37) | NAMPTMAPTMAPK1MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021154902-A1 | COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF | ANIMA BIOTECH INC. (US) | 2021-08-05 | — | — | WO | disclosed |