SCHEMBL29994149

SCHEMBL29994149

Cc1c(C2CCOCC2)[nH]c2ccc(CNC(=O)c3ccnnc3)cc12

nearest known ligand 0.40

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ MAPK1 P28482 6/20 0.40
▸ KDM4E B2RXH2 1/20 0.39
▸ ALDH1A1 P00352 1/20 0.39
▸ L3MBTL1 Q9Y468 1/20 0.39
▸ NAMPT P43490 3/20 0.39
▸ MAPT P10636 2/20 0.39
▸ PROKR1 Q8TCW9 2/20 0.39
▸ NPC1 O15118 1/20 0.38
▸ RAB9A P51151 1/20 0.38
▸ MAOB P27338 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23707316 1.00 MAPK1 (0.40) MAPK1KDM4EALDH1A1L3MBTL1NAMPT
SCHEMBL29993572 0.85 MAPK1 (0.38) MAPK1KDM4EALDH1A1L3MBTL1NAMPT
SCHEMBL23704317 0.85 MAPK1 (0.38) MAPK1KDM4EALDH1A1L3MBTL1NAMPT
SCHEMBL23707303 0.84 NAMPT (0.40) MAPK1KDM4EALDH1A1NAMPTMAPT
SCHEMBL23704277 0.83 MAPT (0.43) KDM4EALDH1A1L3MBTL1MAPT
SCHEMBL23704137 0.83 P2RX3 (0.47) MAPK1KDM4EALDH1A1L3MBTL1NAMPT
SCHEMBL23704132 0.83 UCHL1 (0.44) MAPK1NAMPTMAPT
SCHEMBL23707334 0.83 PROKR1 (0.38) KDM4EALDH1A1L3MBTL1NAMPTMAPT
SCHEMBL23704107 0.83 ALDH1A1 (0.37) MAPK1KDM4EALDH1A1L3MBTL1NAMPT
SCHEMBL29994016 0.83 ALDH1A1 (0.37) MAPK1KDM4EALDH1A1L3MBTL1NAMPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115052860-B Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2024-06-21 — — CN disclosed
EP-4097084-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF Anima Biotech Inc. (US) 2022-12-07 — — EP disclosed
CN-115052860-A Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2022-09-13 — — CN disclosed
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