SCHEMBL23707336

SCHEMBL23707336

Cc1c(C2CCOCC2)[nH]c2ccc(CNC(=O)c3ncnn3C)cc12

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CHRNA7 P36544 1/20 0.38
▸ EGFR P00533 1/20 0.38
▸ CDK2 P24941 1/20 0.38
▸ MAPT P10636 5/20 0.37
▸ ALDH1A1 P00352 5/20 0.37
▸ MEN1 O00255 3/20 0.37
▸ KMT2A Q03164 3/20 0.37
▸ KDM4E B2RXH2 3/20 0.37
▸ CASP1 P29466 1/20 0.37
▸ CASP7 P55210 1/20 0.37
▸ HSD17B10 Q99714 1/20 0.37
▸ TLR9 Q9NR96 2/20 0.36
▸ TLR8 Q9NR97 2/20 0.36
▸ TLR7 Q9NYK1 2/20 0.36
▸ GAA P10253 2/20 0.35
▸ L3MBTL1 Q9Y468 1/20 0.35
▸ LIPG Q9Y5X9 1/20 0.34
▸ MAPK1 P28482 1/20 0.34
▸ HPGD P15428 2/20 0.34
▸ NPC1 O15118 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23707319 0.86 TP53 (0.44) CHRNA7EGFRCDK2MAPTALDH1A1
SCHEMBL23707399 0.84 LMNA (0.41) CHRNA7EGFRCDK2MAPTALDH1A1
SCHEMBL23707334 0.83 PROKR1 (0.38) CHRNA7EGFRCDK2MAPTALDH1A1
SCHEMBL23704355 0.83 L3MBTL1 (0.41) CHRNA7EGFRCDK2MAPTALDH1A1
SCHEMBL23707384 0.82 MAPT (0.37) CHRNA7EGFRCDK2MAPTALDH1A1
SCHEMBL23704277 0.82 MAPT (0.43) CHRNA7EGFRCDK2MAPTALDH1A1
SCHEMBL23707383 0.81 MMP13 (0.41) CHRNA7EGFRCDK2MAPTALDH1A1
SCHEMBL23707337 0.81 GLS (0.43) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL29994245 0.81 NAMPT (0.37) CHRNA7MAPTALDH1A1MEN1KMT2A
SCHEMBL23707340 0.80 MAPT (0.38) CHRNA7EGFRCDK2MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115052860-B Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2024-06-21 — — CN disclosed
EP-4097084-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF Anima Biotech Inc. (US) 2022-12-07 — — EP disclosed
CN-115052860-A Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2022-09-13 — — CN disclosed
WO-2021154902-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2021-08-05 — — WO disclosed
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