SCHEMBL23704355

SCHEMBL23704355

Cc1cc(C(=O)NCc2ccc3[nH]c(C4CCOCC4)c(C)c3c2)n(C)n1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 2/20 0.41
▸ MEN1 O00255 3/20 0.41
▸ KMT2A Q03164 3/20 0.41
▸ KDM4E B2RXH2 2/20 0.41
▸ TDP1 Q9NUW8 1/20 0.41
▸ GALR3 O60755 1/20 0.40
▸ RAB9A P51151 1/20 0.40
▸ ALDH1A1 P00352 3/20 0.39
▸ MAPT P10636 4/20 0.38
▸ CASP1 P29466 1/20 0.38
▸ CASP7 P55210 1/20 0.38
▸ HSD17B10 Q99714 1/20 0.38
▸ EED O75530 1/20 0.37
▸ RBBP4 Q09028 1/20 0.37
▸ SUZ12 Q15022 1/20 0.37
▸ EZH2 Q15910 1/20 0.37
▸ AEBP2 Q6ZN18 1/20 0.37
▸ CDK2 P24941 3/20 0.37
▸ CCNE1 P24864 2/20 0.37
▸ GSK3B P49841 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23704241 0.90 L3MBTL1 (0.39) L3MBTL1MEN1KMT2AKDM4EGALR3
SCHEMBL23707319 0.88 TP53 (0.44) L3MBTL1MEN1KMT2AKDM4EALDH1A1
SCHEMBL23707334 0.88 PROKR1 (0.38) L3MBTL1MEN1KMT2AKDM4EGALR3
SCHEMBL23707383 0.84 MMP13 (0.41) L3MBTL1MEN1KMT2AKDM4ERAB9A
SCHEMBL23707336 0.83 CHRNA7 (0.38) L3MBTL1MEN1KMT2AKDM4ERAB9A
SCHEMBL23707384 0.83 MAPT (0.37) L3MBTL1MEN1KMT2AKDM4EALDH1A1
SCHEMBL23707399 0.83 LMNA (0.41) MEN1KMT2AKDM4EALDH1A1MAPT
SCHEMBL23704277 0.83 MAPT (0.43) L3MBTL1MEN1KMT2AKDM4EALDH1A1
SCHEMBL23707385 0.81 RAB9A (0.37) L3MBTL1MEN1KMT2AKDM4ERAB9A
SCHEMBL29994016 0.80 ALDH1A1 (0.37) L3MBTL1MEN1KMT2AKDM4ERAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115052860-B Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2024-06-21 — — CN disclosed
EP-4097084-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF Anima Biotech Inc. (US) 2022-12-07 — — EP disclosed
CN-115052860-A Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2022-09-13 — — CN disclosed
WO-2021154902-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2021-08-05 — — WO disclosed
WO-2021154902-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2021-08-05 — — WO disclosed
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