Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | CASP9 | P55211 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15550254 | 0.84 | USP2 (0.53) | MAPTALDH1A1KDM4EHSD17B10POLB | |
| SCHEMBL23708146 | 0.77 | RARA (0.51) | BACE1ALDH1A1KDM4EHPGDCASP7 | |
| SCHEMBL26774619 | 0.77 | LIPG (0.45) | MAPTALDH1A1KDM4EHPGDTP53 | |
| SCHEMBL23708497 | 0.77 | LIPG (0.45) | MAPTALDH1A1KDM4EHPGDTP53 | |
| SCHEMBL26774623 | 0.77 | LIPG (0.45) | MAPTALDH1A1KDM4EHPGDTP53 | |
| SCHEMBL15819956 | 0.76 | ALDH1A1 (0.57) | MAPTALDH1A1POLBLMNASMN1; SMN2 | |
| SCHEMBL12953426 | 0.76 | ESR1 (0.52) | MAPTALDH1A1KDM4EHPGDCASP3 | |
| SCHEMBL23708324 | 0.74 | ALDH1A1 (0.57) | MAPTALDH1A1KDM4EHPGDCASP7 | |
| SCHEMBL29935380 | 0.74 | LIPG (0.61) | — | |
| SCHEMBL8133261 | 0.73 | HTR1A (0.54) | MAPTALDH1A1HSD17B10USP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021154966-A1 | COMPOUNDS AND COMPOSITIONS FOR USE IN TREATING SKIN DISORDERS | KAMARI PHARMA LTD. (IL) | 2021-08-05 | — | — | WO | disclosed |