Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 4/20 | 0.51 |
| ▸ | RARB | P10826 | 4/20 | 0.51 |
| ▸ | RARG | P13631 | 4/20 | 0.51 |
| ▸ | BACE1 | P56817 | 2/20 | 0.44 |
| ▸ | GBA1 | P04062 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | LTA4H | P09960 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23708324 | 0.79 | ALDH1A1 (0.57) | GBA1ALDH1A1KDM4ESMN1; SMN2HRH1 | |
| SCHEMBL29763755 | 0.79 | RARG (0.81) | RARARARBRARGGBA1HSD17B10 | |
| SCHEMBL23708144 | 0.77 | MAPT (0.46) | BACE1ALDH1A1LMNAKDM4EHTT | |
| SCHEMBL23708148 | 0.73 | ALOX5 (0.52) | BACE1GBA1ALDH1A1LMNAKDM4E | |
| SCHEMBL23708307 | 0.73 | ALDH1A1 (0.40) | ALDH1A1LTA4HLMNAHRH3KDM4E | |
| SCHEMBL7055686 | 0.72 | HTR1A (0.50) | LMNAHTTSMN1; SMN2 | |
| SCHEMBL8342129 | 0.72 | POLB (0.54) | ALDH1A1KDM4ESMN1; SMN2L3MBTL1KMT2A | |
| SCHEMBL23708502 | 0.70 | KEAP1 (0.56) | ALDH1A1LMNAKDM4EHTTSMN1; SMN2 | |
| SCHEMBL23708081 | 0.70 | KDM4E (0.43) | ALDH1A1KDM4ESMN1; SMN2L3MBTL1HPGD | |
| SCHEMBL23708171 | 0.70 | NCF1 (0.48) | BACE1ALDH1A1LMNAHRH3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021154966-A1 | COMPOUNDS AND COMPOSITIONS FOR USE IN TREATING SKIN DISORDERS | KAMARI PHARMA LTD. (IL) | 2021-08-05 | — | — | WO | disclosed |