Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 2/20 | 0.33 |
| ▸ | NOS1 | P29475 | 2/20 | 0.33 |
| ▸ | NOS2 | P35228 | 2/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18899507 | 0.81 | TRPA1 (0.45) | TRPA1ALDH1A1SLC18A3ESR2ESR1 | |
| SCHEMBL21559944 | 0.81 | TRPA1 (0.41) | TRPA1ESR2ESR1 | |
| SCHEMBL23713624 | 0.81 | TRPA1 (0.41) | TRPA1ESR2ESR1 | |
| SCHEMBL8718208 | 0.81 | TRPA1 (0.61) | TRPA1SLC18A3 | |
| SCHEMBL23713634 | 0.80 | TRPA1 (0.41) | TRPA1DDB1CRBNKDM4EMAPT | |
| SCHEMBL3484987 | 0.75 | SLC18A3 (0.52) | ALDH1A1SLC18A3ESR2ESR1DDB1 | |
| SCHEMBL1064153 | 0.75 | SLC18A3 (0.56) | L3MBTL1SLC18A3ESR2KDM4EMAPT | |
| SCHEMBL23192020 | 0.73 | SLC18A3 (0.55) | ALDH1A1L3MBTL1SLC18A3ESR2KDM4E | |
| SCHEMBL21449754 | 0.73 | SLC18A3 (0.55) | ALDH1A1L3MBTL1SLC18A3ESR2KDM4E | |
| SCHEMBL22291709 | 0.73 | SLC18A3 (0.55) | ALDH1A1L3MBTL1SLC18A3ESR2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11077098-B2 | Opioid receptor ligands and methods of using and making same | TREVENA, INC. (US) | 2021-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11077098-B2 | Opioid receptor ligands and methods of using and making same | OPRL1, OPRK1, OPRM1 | TRPA1 216/4885ALDH1A1 1225/4885L3MBTL1 1762/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.