Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23713609 | 0.81 | TRPA1 (0.41) | TRPA1ESR2ESR1 | |
| SCHEMBL21559944 | 0.81 | TRPA1 (0.41) | TRPA1ESR2ESR1 | |
| SCHEMBL18899507 | 0.81 | TRPA1 (0.45) | TRPA1ESR2ESR1 | |
| SCHEMBL8718208 | 0.81 | TRPA1 (0.61) | TRPA1 | |
| SCHEMBL10012147 | 0.73 | HTT (0.44) | ESR2 | |
| SCHEMBL8718206 | 0.72 | TRPA1 (0.50) | TRPA1ESR2ESR1 | |
| SCHEMBL23713634 | 0.69 | TRPA1 (0.41) | TRPA1 | |
| SCHEMBL19232345 | 0.67 | ESR2 (0.40) | ESR2ESR1 | |
| SCHEMBL8718213 | 0.64 | HTR2C (0.47) | TRPA1 | |
| SCHEMBL19027310 | 0.63 | ALDH1A1 (0.41) | TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11077098-B2 | Opioid receptor ligands and methods of using and making same | TREVENA, INC. (US) | 2021-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11077098-B2 | Opioid receptor ligands and methods of using and making same | OPRL1, OPRK1, OPRM1 | TRPA1 216/4885ESR2 326/4885ESR1 570/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.